Nanoscience and Technology Interdisciplinary Program, Chulalongkorn University, Phayathai Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.
Program in Petrochemistry and Polymer Science, Faculty of Science, Chulalongkorn University, Phayathai Road, Wangmai, Pathumwan, Bangkok, 10330, Thailand.
Carbohydr Polym. 2021 Mar 15;256:117506. doi: 10.1016/j.carbpol.2020.117506. Epub 2020 Dec 13.
Direct deposition of the negatively charged polyelectrolyte, carboxymethyl cellulose (CMC), into a bacterial cellulose (BC) matrix was used as a simple route to fabricate a re-swellable and biocompatible cellulose-based hydrogel. As a result of this non-destructive approach, the physical and mechanical property of the original BC were well-preserved within the resulting BC/CMC hydrogel. As a BC/CMC-based colorimetric pH sensor, it exhibited a rapid response with an easy color differentiation between each pH by the naked eye, and wide linear range of pH 4.0-9.0 with good linearity. For the detection of glucose in sweat, the BC/CMC-based colorimetric glucose sensor provided a low limit of detection (25 μM) with a wide linear detection range (0.0-0.5 mM) and high accuracy. These BC/CMC based sensors could potentially be applied as non-invasive semi-quantitative sensors for on-skin health monitoring.
将带负电荷的聚电解质羧甲基纤维素（CMC）直接沉积到细菌纤维素（BC）基质中，被用作制备可再溶胀和生物相容的纤维素基水凝胶的简单方法。由于这种非破坏性方法，原始 BC 的物理和机械性能在所得 BC/CMC 水凝胶中得到了很好的保留。作为基于 BC/CMC 的比色 pH 传感器，它通过肉眼在每个 pH 值之间具有快速响应和易于区分的颜色，并且具有宽线性范围 pH4.0-9.0 和良好的线性度。对于汗液中葡萄糖的检测，基于 BC/CMC 的比色葡萄糖传感器具有低检测限（25μM），宽线性检测范围（0.0-0.5mM）和高精度。这些基于 BC/CMC 的传感器有可能被用作非侵入性半定量传感器，用于皮肤健康监测。
