Physical Environment Group, Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Road, Xiamen, 361021, People's Republic of China.
Xiamen Key Laboratory of Physical Environment, 1799 Jimei Road, Xiamen, 361021, People's Republic of China.
Sci Rep. 2021 Jan 22;11(1):2123. doi: 10.1038/s41598-020-80830-z.
Electromagnetic radiation is an important environmental factor. It has a potential threat to public health and ecological environment. However, the mechanism by which electromagnetic radiation exerts these biological effects remains unclear. In this study, the effect of Microcystis aeruginosa under electromagnetic radiation (1.8 GHz, 40 V/m) was studied by using transcriptomics. A total of 306 differentially expressed genes, including 121 upregulated and 185 downregulated genes, were obtained in this study. The differentially expressed genes were significantly enriched in the ribosome, oxidative phosphorylation and carbon fixation pathways, indicating that electromagnetic radiation may inhibit protein synthesis and affect cyanobacterial energy metabolism and photosynthesis. The total ATP synthase activity and ATP content significantly increased, whereas HK-ATPase activity showed no significant changes. Our results suggest that the energy metabolism pathway may respond positively to electromagnetic radiation. In the future, systematic studies on the effects of electromagnetic radiation based on different intensities, frequencies, and exposure times are warranted; to deeply understand and reveal the target and mechanism of action of electromagnetic exposure on organisms.
电磁辐射是一种重要的环境因素，它对公众健康和生态环境具有潜在威胁。然而，电磁辐射发挥这些生物效应的机制尚不清楚。在本研究中，使用转录组学研究了电磁辐射（1.8GHz，40V/m）对铜绿微囊藻的影响。本研究共获得了 306 个差异表达基因，其中 121 个上调基因和 185 个下调基因。差异表达基因在核糖体、氧化磷酸化和碳固定途径中显著富集，表明电磁辐射可能抑制蛋白质合成，并影响蓝藻的能量代谢和光合作用。总 ATP 合酶活性和 ATP 含量显著增加，而 HK-ATPase 活性没有显著变化。我们的结果表明，能量代谢途径可能对电磁辐射做出积极响应。未来需要基于不同的强度、频率和暴露时间进行电磁辐射影响的系统研究，以深入理解和揭示电磁辐射对生物体的作用靶点和机制。
