Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Solna, Sweden.
Eur J Trauma Emerg Surg. 2022 Feb;48(1):293-298. doi: 10.1007/s00068-020-01596-7. Epub 2021 Jan 23.
There are few studies on incidence rates, treatment and outcomes for peri-implant femoral fractures (PIFF) in the proximity of osteosynthesis. The purpose of this study was to investigate the incidence of PIFF following osteosynthesis of proximal femoral fractures.
This retrospective cohort study comprised a consecutive series of hip fracture patients aged 50 years or older and operated with osteosynthesis between 2003 and 2015. Patients were followed-up until 2018, removal of implants or death, for a mean of 4 years (range 0-15). Data on age, sex, housing, hip complications, and reoperations were recorded. The risk of PIFFs was assessed using Cox proportional hazards regression analysis. In patients with two fractures during the study period, only the first fracture was included.
A total of 1965 osteosynthesis procedures were performed, of which 382 were cephalomedullary nails (CMN), 933 sliding hip devices (SHD) and 650 pins. Mean age was 80 years (range 50-104), 65% of patients were women. A total of 41 PIFFs occurred during the study period. The cumulative incidence of peri-implant fractures was 0.8% for CMN, 2.7% (HR 2.995% CI, 0.87-9.6, p = 0.08) for SHD and 2.0% (HR 2.3 95% CI, 0.6-8.1, p = 0.2) for pins. PIFFs occurred after a mean of 27 months (range 0-143). The 1-year mortality was 34% following PIFF. The majority was treated surgically (66%, 27/41) and the reoperation rate was 15% (4/27).
In this retrospective cohort study, in contrast to previous reports, we found a tendency to a higher cumulative incidence of PIFFs for SHD compared to modern CMN. Our results show cumulative incidences of PIFFs comparable to those described for periprosthetic femur fractures after hip arthroplasty for femoral neck fracture.
在骨接合附近,有关种植体周围股骨骨折(PIFF)的发生率、治疗和结果的研究较少。本研究的目的是探讨股骨近端骨折骨接合后 PIFF 的发生率。
本回顾性队列研究纳入了 2003 年至 2015 年间接受骨接合治疗且年龄在 50 岁及以上的髋部骨折患者的连续系列。患者随访至 2018 年,或至植入物取出或死亡,平均随访时间为 4 年(范围 0-15 年)。记录年龄、性别、住房、髋部并发症和再次手术等数据。使用 Cox 比例风险回归分析评估 PIFF 风险。在研究期间发生两次骨折的患者中,仅纳入第一次骨折。
共进行了 1965 次骨接合手术,其中包括 382 例顺行髓内钉(CMN)、933 例滑动髋部装置(SHD)和 650 例钢针。患者平均年龄为 80 岁(范围 50-104 岁),65%为女性。研究期间共发生 41 例 PIFF。CMN 的累积骨折发生率为 0.8%,SHD 为 2.7%(HR 2.995%CI,0.87-9.6,p=0.08),钢针为 2.0%(HR 2.3 95%CI,0.6-8.1,p=0.2)。PIFF 发生的平均时间为 27 个月(范围 0-143 个月)。PIFF 后 1 年死亡率为 34%。大多数患者接受了手术治疗(66%,27/41),再次手术率为 15%(4/27)。
在本回顾性队列研究中,与之前的报告相反,我们发现 SHD 的 PIFF 累积发生率较现代 CMN 有增高趋势。我们的结果显示 PIFF 的累积发生率与髋关节置换术后股骨颈骨折患者描述的假体周围股骨骨折相似。