Davies P S, Valley R, Preece M A
Department of Growth and Development, Institute of Child Health, London.
Arch Dis Child. 1988 Feb;63(2):130-5. doi: 10.1136/adc.63.2.130.
The pattern of growth and development of 18 adolescent children with the Silver-Russell syndrome was studied. Mature height was about -3.6 standard deviation scores in both sexes. This is comparable to the height reduction at diagnosis, which has been reported previously. The pattern of puberty and adolescent growth was essentially normal and occurred at a marginally earlier time than normal, although in this small series the differences were not significant. In the girls there was a tendency to gain subcutaneous fat after puberty. This trend was not apparent in the boys.
对18名患有Silver-Russell综合征的青少年儿童的生长发育模式进行了研究。两性的成熟身高均约为-3.6标准差分数。这与先前报道的诊断时的身高降低情况相当。青春期和青少年生长模式基本正常，且比正常情况略早出现，不过在这个小样本系列中，差异并不显著。在女孩中，青春期后有增加皮下脂肪的趋势。这种趋势在男孩中不明显。
