Bowling F, Cleghorn G, Chester A, Curran J, Griffin B, Prado J, Francis P, Shepherd R
Neonatal Screening Laboratory, State Department of Health, Royal Children's Hospital, Brisbane, Australia.
Arch Dis Child. 1988 Feb;63(2):196-8. doi: 10.1136/adc.63.2.196.
Two groups of patients with cystic fibrosis were compared. The screened group, detected with an improved neonatal screening assay for immunoreactive trypsin, developed fewer chest infections requiring treatment and gained more weight than the unscreened group. Early diagnosis by screening seems to affect early morbidity.
对两组囊性纤维化患者进行了比较。通过改进的新生儿免疫反应性胰蛋白酶筛查检测法检测出的筛查组,需要治疗的胸部感染较少,体重增加也比未筛查组更多。通过筛查进行早期诊断似乎会影响早期发病率。