Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Master of Science in Advanced General Dentistry, Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Thailand.
Cleft Palate Craniofac J. 2021 Nov;58(11):1430-1437. doi: 10.1177/1055665620987677. Epub 2021 Jan 25.
Two main objectives were established. First objective was to determine the prevalence of the cleft lip and/or cleft palate (CL/P) in Thailand from 2012 to 2015 using the orofacial clefts (OFCs) registry and civil registration. Second objective was to conduct a quality control of this OFC registry especially for the Birth Defects Registration (BDR).
Registry-based survey.
Analyzing data from the Thailand National Health Security Office.
Registered patients with CL/P in Thailand from 2012 to 2015.
None.
Duplicated records were verified using National Identity Number (Thai ID#) and date of birth. The prevalence of CL/P and specific phenotypes was then calculated. From this prevalence estimate method, quality assurance of the OFCs registry was possible.
For the main outcome, the population-weighted pool prevalence of CL/P was 2.14 per 1000 live births (95% confidence interval of 2.08-2.20). Thai ID# and expense reimbursement systems were the main factors driving this cases capturing. However, this OFCs registration still requires active case finding with clinical verification, improvement of staff training and databases networking.
This study reported a very high CL/P prevalence of Thailand. Strengths and limitations of these OFCs registry and BDR were described.
确立了两个主要目标。首先，通过口面裂（OFCs）登记和公民登记，确定 2012 年至 2015 年泰国唇裂和/或腭裂（CL/P）的流行率。其次，对 OFC 登记进行质量控制，特别是对出生缺陷登记（BDR）进行质量控制。
基于登记的调查。
分析泰国国家健康保障办公室的数据。
2012 年至 2015 年在泰国登记的 CL/P 患者。
无。
使用国家身份证号码（泰国身份证号码）和出生日期验证重复记录。然后计算 CL/P 和特定表型的患病率。通过这种患病率估计方法，可以对 OFC 登记进行质量保证。
对于主要结局，CL/P 的人群加权总患病率为每 1000 例活产儿 2.14 例（95%置信区间为 2.08-2.20）。泰国身份证号码和报销系统是发现这些病例的主要因素。然而，这种 OFC 登记仍然需要通过临床验证进行主动病例发现，提高工作人员的培训和数据库联网。
本研究报告了泰国非常高的 CL/P 患病率。描述了这些 OFC 登记和 BDR 的优势和局限性。
