Shoenut J P, Trenholm B G, Micflikier A B, Teskey J M
Department of Medicine, St. Boniface General Hospital, Winnipeg, Man, Canada.
Ann Thorac Surg. 1988 Mar;45(3):303-5. doi: 10.1016/s0003-4975(10)62467-8.
Five patients with achalasia who had not had an operation underwent esophageal manometry and 24-hour, ambulatory pH monitoring to determine the pattern and extent of esophageal reflux. One patient had reflux within normal limits. In 2 patients, reflux occurred 0.5% of the total time and no episodes of supine reflux were recorded. In the 2 remaining patients, reflux was measured 16.8% and 55.3% of the total time; however, in both patients, these results were influenced by lengthy bouts of supine reflux. These indices of reflux were not influenced by differences in resting lower esophageal sphincter tone, position, or length. Twenty-four-hour esophageal pH monitoring can be useful in the preoperative assessment of patients with achalasia, and the information obtained might influence the choice of operative procedure.
5例未经手术治疗的贲门失弛缓症患者接受了食管测压及24小时动态pH监测，以确定食管反流的模式和程度。1例患者反流在正常范围内。2例患者反流发生时间占总时间的0.5%，未记录到仰卧位反流发作。其余2例患者反流时间分别占总时间的16.8%和55.3%；然而，在这2例患者中，这些结果均受长时间仰卧位反流的影响。这些反流指标不受静息时食管下括约肌张力、位置或长度差异的影响。24小时食管pH监测对贲门失弛缓症患者的术前评估可能有用，所获得的信息可能会影响手术方式的选择。
