Tahouri Tahmineh, Mahdavi Mohammad, Rezaei-Kalantari Kiara, Shahzadi Hossein
Department of Pediatric Cardiology, Iran University of Medical Science, Tehran, Iran.
Cardiol Young. 2021 May;31(5):845-847. doi: 10.1017/S1047951120004862. Epub 2021 Jan 25.
Hypereosinophilic syndrome is defined as persistent eosinophilia in the blood for more than 6 months, without any identifiable cause and with end-organ involvement evidence. Cardiac manifestations of HES include heart failure due to restrictive cardiomyopathy, arrhythmia, intraventricular thrombosis, and coronary artery involvement occurs frequently. In rare instances, coronary ectasia, aneurysms, or dissection can occur and cause morbidity and mortality in these patients.A coronary aneurysm occurs rarely in adult patients with HES but to our knowledge, this is the first report of this association in a 14-year-old boy who was presented to us as coronary aneurysm due to hypereosinophilic syndrome.
高嗜酸性粒细胞综合征定义为血液中嗜酸性粒细胞持续增多超过6个月，无任何可识别病因且有终末器官受累证据。高嗜酸性粒细胞综合征的心脏表现包括限制性心肌病导致的心力衰竭、心律失常、心室内血栓形成，且冠状动脉受累也较为常见。在罕见情况下，可出现冠状动脉扩张、动脉瘤或夹层，从而导致这些患者发病和死亡。冠状动脉瘤在成年高嗜酸性粒细胞综合征患者中很少见，但据我们所知，这是首例关于一名14岁男孩因高嗜酸性粒细胞综合征出现冠状动脉瘤的报道。
