新冠病毒疫苗在我们移植受者中的应用：现在是时候了。
COVID-19 vaccination in our transplant recipients: The time is now.
机构信息
Division of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California.
Departments of Internal Medicine; Microbiology and Immunology, The University of Michigan, Ann Arbor, Michigan.
出版信息
J Heart Lung Transplant. 2021 Mar;40(3):169-171. doi: 10.1016/j.healun.2020.12.009. Epub 2021 Jan 2.
Abstract
We are entering 2021 with an expanding and effective COVID-19 vaccine armamentarium. Recent interim results from COVID-19 vaccine trials, including more than 80,000 participants worldwide, demonstrate remarkable efficacy and low rate of serious adverse events. Based on experience with other vaccines in transplant recipients and knowing the risk of severe COVID-19 in this population, we believe that COVID-19 vaccines provide potential benefit with minimal risk. We strongly support and encourage COVID-19 vaccination of our transplant recipients.
摘要
我们正带着不断扩大且有效的 COVID-19 疫苗武器进入 2021 年。最近 COVID-19 疫苗试验的中期结果，包括全球超过 80000 名参与者，显示出显著的疗效和低严重不良事件发生率。基于在移植受者中使用其他疫苗的经验，并且了解到该人群中 COVID-19 严重感染的风险，我们认为 COVID-19 疫苗具有潜在的益处且风险最小。我们强烈支持并鼓励我们的移植受者接种 COVID-19 疫苗。
相似文献
1
COVID-19 vaccination in our transplant recipients: The time is now.新冠病毒疫苗在我们移植受者中的应用：现在是时候了。
J Heart Lung Transplant. 2021 Mar;40(3):169-171. doi: 10.1016/j.healun.2020.12.009. Epub 2021 Jan 2.
2
Humoral Response after SARS-CoV-2 mRNA Vaccination in a Cohort of Hemodialysis Patients and Kidney Transplant Recipients.血液透析患者和肾移植受者队列中 SARS-CoV-2 mRNA 疫苗接种后的体液反应。
J Am Soc Nephrol. 2021 Sep;32(9):2153-2158. doi: 10.1681/ASN.2021040490. Epub 2021 Jun 16.
3
Coronavirus disease 2019 vaccination in transplant recipients.新型冠状病毒病 2019 疫苗接种在移植受者中的应用。
Curr Opin Infect Dis. 2021 Aug 1;34(4):275-287. doi: 10.1097/QCO.0000000000000739.
4
SARS-CoV-2 vaccination in solid-organ transplant recipients: What the clinician needs to know.SARS-CoV-2 疫苗接种在实体器官移植受者中的应用：临床医生需要了解的知识。
Transpl Int. 2021 Oct;34(10):1776-1788. doi: 10.1111/tri.14029. Epub 2021 Sep 20.
5
What Are COVID-19 Vaccines?什么是新冠疫苗？
Am J Respir Crit Care Med. 2021 May 1;203(9):P22-P23. doi: 10.1164/rccm.2021C2.
6
SARS-CoV-2 Vaccines in Kidney Transplant Recipients: Will They Be Safe and Effective and How Will We Know?肾移植受者的新冠病毒2型疫苗：它们会安全有效吗？我们又如何得知？
J Am Soc Nephrol. 2021 May 3;32(5):1021-1024. doi: 10.1681/ASN.2021010023. Epub 2021 Mar 24.
7
Immunogenicity of SARS-CoV-2 mRNA vaccine in solid organ transplant recipients.SARS-CoV-2 mRNA 疫苗在实体器官移植受者中的免疫原性。
J Intern Med. 2021 Dec;290(6):1264-1267. doi: 10.1111/joim.13361. Epub 2021 Aug 9.
8
SARS-CoV-2 Vaccination Rates and Uptake of Tixagevimab-Cilgavimab Among a Cohort of Pediatric Solid Organ Transplant Recipients.SARS-CoV-2 疫苗接种率及替沙格韦单抗-西加韦单抗在儿科实体器官移植受者队列中的应用。
Clin Transplant. 2024 Jul;38(7):e15407. doi: 10.1111/ctr.15407.
9
Ethical considerations regarding COVID-19 vaccination for transplant candidates and recipients.关于 COVID-19 疫苗接种用于移植候选者和受者的伦理考虑。
Clin Transplant. 2021 Oct;35(10):e14421. doi: 10.1111/ctr.14421. Epub 2021 Jul 19.
10
Update on COVID-19 vaccination in pediatric solid organ transplant recipients.儿童实体器官移植受者 COVID-19 疫苗接种的最新进展。
Pediatr Transplant. 2022 Aug;26(5):e14235. doi: 10.1111/petr.14235. Epub 2022 Jan 20.
引用本文的文献
1
[SEPAR Recommendations for COVID-19 Vaccination in Patients With Respiratory Diseases].[呼吸系统疾病患者新冠病毒疫苗接种的SEPAR建议]
Open Respir Arch. 2021 Mar 22;3(2):100097. doi: 10.1016/j.opresp.2021.100097. eCollection 2021 Apr-Jun.
2
Effects of public health interventions and zero COVID policy on paediatric diseases: A Southern China study.公共卫生干预措施及新冠清零政策对儿科疾病的影响：一项中国南方地区的研究。
J Glob Health. 2024 Jan 26;14:05011. doi: 10.7189/jogh.14.05011.
3
Investigation on the hesitancy of COVID-19 vaccination among liver transplant recipients: A cross-sectional study in China.中国一项关于肝移植受者对 COVID-19 疫苗犹豫的横断面研究。
Front Public Health. 2022 Dec 15;10:1014942. doi: 10.3389/fpubh.2022.1014942. eCollection 2022.
4
Donor heart selection: Evidence-based guidelines for providers.供心选择：供者评估的循证临床实践指南
J Heart Lung Transplant. 2023 Jan;42(1):7-29. doi: 10.1016/j.healun.2022.08.030. Epub 2022 Sep 20.
5
Incidence of COVID-19 and Identification of Possible Risk Factors Associated with COVID-19 in Acute Renal Transplant Recipients in Pakistan.巴基斯坦急性肾移植受者 COVID-19 的发病率及与 COVID-19 相关的可能危险因素的鉴定。
Ann Transplant. 2022 Oct 4;27:e937688. doi: 10.12659/AOT.937688.
6
Immunogenicity and safety of two-dose SARS-CoV-2 vaccination different platforms in kidney transplantation recipients.两种不同平台的 SARS-CoV-2 疫苗接种在肾移植受者中的免疫原性和安全性。
Front Immunol. 2022 Sep 16;13:951576. doi: 10.3389/fimmu.2022.951576. eCollection 2022.
7
Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination.严重 COVID-19 患者外周血单个核细胞反应的转录组分析揭示了调控蛋白质泛素化的关键基因。
Med Sci Monit. 2022 Aug 29;28:e937532. doi: 10.12659/MSM.937532.
8
Humoral response to different SARS-CoV-2 vaccines in orthotopic liver transplant recipients.肝移植受者对不同 SARS-CoV-2 疫苗的体液免疫反应。
Vaccine. 2022 Sep 9;40(38):5621-5630. doi: 10.1016/j.vaccine.2022.08.027. Epub 2022 Aug 22.
9
Ongoing Mycophenolate Treatment Impairs Anti-SARS-CoV-2 Vaccination Response in Patients Affected by Chronic Inflammatory Autoimmune Diseases or Liver Transplantation Recipients: Results of the RIVALSA Prospective Cohort.正在进行的霉酚酸治疗可损害慢性炎症性自身免疫性疾病患者或肝移植受者的抗 SARS-CoV-2 疫苗接种反应：RIVALSA 前瞻性队列研究的结果。
Viruses. 2022 Aug 12;14(8):1766. doi: 10.3390/v14081766.
10
Vaccination Against SARS-CoV-2 in Lung Transplant Recipients: Immunogenicity, Efficacy and Safety.新型冠状病毒疫苗在肺移植受者中的免疫原性、疗效和安全性。
Front Immunol. 2022 Jun 1;13:906225. doi: 10.3389/fimmu.2022.906225. eCollection 2022.
本文引用的文献
1
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.ChAdOx1 nCoV-19 疫苗（阿斯利康）对 SARS-CoV-2 的安全性和有效性：巴西、南非和英国四项随机对照试验的中期分析。
Lancet. 2021 Jan 9;397(10269):99-111. doi: 10.1016/S0140-6736(20)32661-1. Epub 2020 Dec 8.
2
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.BNT162b2 mRNA 新冠病毒疫苗的安全性和有效性。
N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10.
3
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.新型冠状病毒病 2019（COVID-19）的病理生理学、传播、诊断和治疗：综述。
JAMA. 2020 Aug 25;324(8):782-793. doi: 10.1001/jama.2020.12839.
4
Vaccination of solid organ transplant candidates and recipients: Guidelines from the American society of transplantation infectious diseases community of practice.实体器官移植候选人和受者的疫苗接种：美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13563. doi: 10.1111/ctr.13563. Epub 2019 Jun 5.
5
Immunogenicity and Safety of the Adjuvanted Recombinant Zoster Vaccine in Chronically Immunosuppressed Adults Following Renal Transplant: A Phase 3, Randomized Clinical Trial.佐剂重组带状疱疹疫苗在慢性免疫抑制的肾移植后成年人中的免疫原性和安全性：一项 3 期、随机临床试验。
Clin Infect Dis. 2020 Jan 2;70(2):181-190. doi: 10.1093/cid/ciz177.
6
Influenza vaccine strategies for solid organ transplant recipients.流感疫苗策略在实体器官移植受者中的应用。
Curr Opin Infect Dis. 2018 Aug;31(4):309-315. doi: 10.1097/QCO.0000000000000461.
7
A Double-Blind, Randomized Trial of High-Dose vs Standard-Dose Influenza Vaccine in Adult Solid-Organ Transplant Recipients.成人实体器官移植受者中高剂量与标准剂量流感疫苗的双盲、随机试验。
Clin Infect Dis. 2018 May 17;66(11):1698-1704. doi: 10.1093/cid/cix1082.
8
Risk of solid organ transplant rejection following vaccination with seasonal trivalent inactivated influenza vaccines in England: A self-controlled case-series.英格兰接种季节性三价灭活流感疫苗后实体器官移植排斥反应的风险：一项自我对照病例系列研究。
Vaccine. 2016 Jun 30;34(31):3598-606. doi: 10.1016/j.vaccine.2016.05.016. Epub 2016 May 20.
Zotero 插件