Summers M N, Haley W E, Reveille J D, Alarcón G S
Department of Psychology, School of Medicine, University of Alabama, Birmingham.
Arthritis Rheum. 1988 Feb;31(2):204-9. doi: 10.1002/art.1780310208.
Sixty-five outpatients with osteoarthritis of the knee and/or hip were assessed using radiographic ratings of disease severity, measures of psychologic coping, and multidimensional clinical outcomes of degree of pain and functional impairment. Disease severity accounted for little of the individual variability in clinical outcomes. Even after controlling for disease severity, psychologic variables remained strong predictors of individual differences in functional impairment and pain. Psychologic processes deserve greater clinical and research attention as potential mediators between disease severity and clinical outcome.
65例膝和/或髋关节骨关节炎门诊患者接受了疾病严重程度的影像学评级、心理应对措施以及疼痛程度和功能障碍的多维度临床结局评估。疾病严重程度在临床结局的个体差异中所占比例很小。即使在控制了疾病严重程度之后，心理变量仍然是功能障碍和疼痛个体差异的有力预测因素。心理过程作为疾病严重程度和临床结局之间的潜在中介因素，值得临床和研究给予更多关注。
