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从垃圾到奢侈品:植物长链非编码RNA在非生物胁迫下DNA甲基化中的潜在作用

From Trash to Luxury: The Potential Role of Plant LncRNA in DNA Methylation During Abiotic Stress.

作者信息

Urquiaga Maria Clara de Oliveira, Thiebaut Flávia, Hemerly Adriana Silva, Ferreira Paulo Cavalcanti Gomes

机构信息

Laboratório de Biologia Molecular de Plantas, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Front Plant Sci. 2021 Jan 6;11:603246. doi: 10.3389/fpls.2020.603246. eCollection 2020.

Abstract

Remarkable progress has been made in elucidating important roles of plant non-coding RNAs. Among these RNAs, long noncoding RNAs (lncRNAs) have gained widespread attention, especially their role in plant environmental stress responses. LncRNAs act at different levels of gene expression regulation, and one of these mechanisms is by recruitment of DNA methyltransferases or demethylases to regulate the target gene transcription. In this mini-review, we highlight the function of lncRNAs, including their potential role in RNA-directed DNA Methylation (RdDM) silencing pathway and their potential function under abiotic stresses conditions. Moreover, we also present and discuss studies of lncRNAs in crops. Finally, we propose a path outlook for future research that may be important for plant breeding.

摘要

在阐明植物非编码RNA的重要作用方面已取得显著进展。在这些RNA中,长链非编码RNA(lncRNA)已受到广泛关注,尤其是它们在植物环境胁迫响应中的作用。lncRNA在基因表达调控的不同水平上发挥作用,其中一种机制是通过招募DNA甲基转移酶或去甲基化酶来调节靶基因转录。在这篇小型综述中,我们重点介绍了lncRNA的功能,包括它们在RNA介导的DNA甲基化(RdDM)沉默途径中的潜在作用以及在非生物胁迫条件下的潜在功能。此外,我们还展示并讨论了作物中lncRNA的研究。最后,我们提出了一条未来研究的路径展望,这可能对植物育种很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/219b/7815527/72857da4b032/fpls-11-603246-g001.jpg

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