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局灶性感染与牙周炎:一篇叙述性报告及新的可能方法

Focal Infection and Periodontitis: A Narrative Report and New Possible Approaches.

作者信息

Rocca Jean-Paul, Fornaini Carlo, Wang Zuomin, Tan Lixin, Merigo Elisabetta

机构信息

Shijiazhuang 2 Hospital, Department of Stomatology (South), Gonguong Road 425, Quoxi District, Shijiazhuang, China.

UFRO dontologie, UPR Micoralis, University Côte d'Azur, 24 Avenue des Diables Bleus, 06354 Nice Cedex, France.

出版信息

Int J Microbiol. 2020 Oct 29;2020:8875612. doi: 10.1155/2020/8875612. eCollection 2020.

Abstract

The "focal infection theory" is a historical concept based on the assumption that some infections may cause chronic and acute diseases in different districts of the body. Its great popularity spanned from 1930 to 1950 when, with the aim to remove all the foci of infection, drastic surgical interventions were performed. Periodontitis, a common oral pathology mainly of bacterial origin, is the most evident example of this phenomenon today: in fact, bacteria are able to migrate, develop and cause health problems such as cardiovascular and respiratory diseases, diabetes, and osteoporosis. The aim of this narrative report is to verify the hypothesis of the association between oral infections and systemic diseases by different ways of approach and, at the same time, to propose new kinds of treatment today made possible by technological progress. The analysis of the literature demonstrated a strong relationship between these conditions, which might be explained on the basis of the recent studies on microbiota movement inside the body. Prevention of the oral infections, as well as of the possible systemic implications, may be successfully performed with the help of new technologies, such as probiotics and laser.

摘要

“病灶感染理论”是一个基于某些感染可能在身体不同部位引发急慢性疾病这一假设的历史概念。它在1930年至1950年期间广受欢迎,当时为了消除所有感染病灶,人们进行了激进的外科手术干预。牙周炎是一种主要由细菌引起的常见口腔疾病,是当今这一现象最明显的例子:事实上,细菌能够迁移、繁殖并引发心血管疾病、呼吸道疾病、糖尿病和骨质疏松症等健康问题。本叙述性报告的目的是通过不同的研究方法验证口腔感染与全身性疾病之间关联的假设,同时提出因技术进步而成为可能的新型治疗方法。文献分析表明这些病症之间存在密切关系,这或许可以基于近期关于微生物群在体内移动的研究得到解释。借助益生菌和激光等新技术,可以成功预防口腔感染以及可能产生的全身性影响。

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本文引用的文献

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[A renewed focus on extra-oral manifestations of oral infections].[对口腔感染口外表现的重新关注]
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