Amsalu Hailemariam, Wondimnew Tesaka, Mateos Tigist, Fekadie Minale, Bogale Gesese
Department of Biomedical Sciences, Mizan-Tepi University, Ethiopia.
Department of Biomedical Sciences, Jimma University, Ethiopia.
J Lipids. 2020 Dec 4;2020:8819749. doi: 10.1155/2020/8819749. eCollection 2020.
Foods fried with oils at streets contain many harmful substances for health. Locally fried foods are consumed commonly in our society, yet their health effect is not studied.
To assess the effect of palm oil-fried street kokor on liver and kidney biomarkers of Swiss Albino mice.
Thirty-two male and female Swiss Albino mice with the age of 10-12 weeks old were divided randomly into four groups of eight members with equal male and female subgroups. The control group (group I) received only a standard pellet, and the experimental groups (group II, group III, and group IV) received 10%, 20%, and 30% kokor of their daily food consumption, respectively. At the end of the 6 week, they were sacrificed by thoracoabdominal incision after anesthetizing by diethyl ether. Blood was taken from each mouse by cardiac puncture and analyzed for liver and kidney function tests.
The serum levels of liver damage biomarkers (alanine transaminase (ALT) and aspartate transaminase (AST)) and kidney damage biomarkers (urea and creatinine) of experimental groups were increased significantly relative to the control groups ( < 0.05). Level of biochemical profiles increased as the dose of kokor increased.
Palm oil-fried street kokor damaged the liver and kidney of the mice, and the damage was exacerbated as the dose of kokor increased.
街头用油炸制的食品含有许多对健康有害的物质。当地油炸食品在我们的社会中普遍食用，但尚未对其健康影响进行研究。
评估棕榈油煎炸的街头可可球对瑞士白化小鼠肝脏和肾脏生物标志物的影响。
将32只10 - 12周龄的雄性和雌性瑞士白化小鼠随机分为四组，每组8只，雌雄亚组数量相等。对照组（第一组）仅给予标准颗粒饲料，实验组（第二组、第三组和第四组）分别给予其每日食物摄入量10%、20%和30%的可可球。在第6周结束时，用乙醚麻醉后通过胸腹切口将它们处死。通过心脏穿刺从每只小鼠采集血液，并进行肝功能和肾功能测试分析。
与对照组相比，实验组肝脏损伤生物标志物（丙氨酸转氨酶（ALT）和天冬氨酸转氨酶（AST））以及肾脏损伤生物标志物（尿素和肌酐）的血清水平显著升高（<0.05）。随着可可球剂量的增加，生化指标水平升高。
棕榈油煎炸的街头可可球损害了小鼠的肝脏和肾脏，并且随着可可球剂量的增加，损害加剧。
