Haikal Ammar, Govil Swati, Anis Arsany, Guma Jenna
Internal Medicine, Hackensack Meridian Medical Center, Hackensack, USA.
Internal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Cureus. 2020 Dec 14;12(12):e12077. doi: 10.7759/cureus.12077.
Dermatomyositis (DM) is an autoimmune inflammatory myopathy characterized by features of a typical rash, proximal muscle weakness, and evidence of muscle inflammation. Acute inflammatory demyelinating polyneuropathy (AIDP) is an autoimmune peripheral nerve disease characterized by myelin damage and progressive areflexic weakness and sensory changes. AIDP can be precipitated by viral infections such as Epstein-Barr virus (EBV). We present a case of DM with rhabdomyolysis and necrotizing features, along with AIDP in the setting of EBV viremia. DM and AIDP rarely coincide together. The patient was treated with a combination therapy of methylprednisolone, azathioprine, and intravenous immunoglobulins (IVIGs), which led to significant improvement in his symptoms.
皮肌炎（DM）是一种自身免疫性炎性肌病，其特征为典型皮疹、近端肌无力以及肌肉炎症证据。急性炎性脱髓鞘性多发性神经病（AIDP）是一种自身免疫性周围神经疾病，其特征为髓鞘损伤、进行性无反射性肌无力和感觉改变。AIDP可由诸如EB病毒（EBV）等病毒感染诱发。我们报告一例伴有横纹肌溶解和坏死特征的皮肌炎病例，同时该患者在EBV病毒血症背景下合并AIDP。皮肌炎和AIDP很少同时出现。该患者接受了甲泼尼龙、硫唑嘌呤和静脉注射免疫球蛋白（IVIG）的联合治疗，症状得到显著改善。
