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甲型肝炎感染并发症:急性炎症性脱髓鞘性多发性神经病病例报告

Complication of Hepatitis A Infection: Case Report of Acute Inflammatory Demyelinating Polyneuropathy.

作者信息

Laursen Daniel, Krug Jeffrey, Wolford Robert

机构信息

University of Illinois College of Medicine - Peoria, Department of Emergency Medicine, Peoria, Illinois. OSF Saint Francis Medical Center, Department of Emergency Medicine, Peoria, Illinois.

出版信息

Clin Pract Cases Emerg Med. 2021 Feb;5(1):113-116. doi: 10.5811/cpcem.2020.9.48827.

DOI:10.5811/cpcem.2020.9.48827
PMID:33560967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7872614/
Abstract

INTRODUCTION

Acute inflammatory demyelinating polyneuropathy (AIDP) is characterized by progressive, mild sensory symptoms and progressive areflexic weakness. It typically follows a gastrointestinal or respiratory infection but has rarely been described after acute viral hepatitis.

CASE REPORT

This is the case of a 59-year-old male who presented to the emergency department after acutely developing progressive neurologic symptoms following a hospitalization for acute hepatitis A. Cerebrospinal fluid analysis revealed albuminocytologic dissociation, and cervical spine magnetic resonance imaging revealed nerve root enhancement.

DISCUSSION

The patient was diagnosed with AIDP, which is the most common subtype of Guillain-Barré syndrome in the United States and Europe. There have been few previously reported cases of AIDP following acute hepatitis A infection.

摘要

引言

急性炎症性脱髓鞘性多发性神经病(AIDP)的特征为进行性、轻度感觉症状和进行性腱反射消失性肌无力。它通常在胃肠道或呼吸道感染后出现,但急性病毒性肝炎后出现的情况很少被描述。

病例报告

这是一名59岁男性的病例,他在因甲型肝炎住院后急性出现进行性神经症状,随后到急诊科就诊。脑脊液分析显示蛋白细胞分离,颈椎磁共振成像显示神经根强化。

讨论

该患者被诊断为AIDP,这是美国和欧洲格林-巴利综合征最常见的亚型。先前很少有甲型肝炎感染后发生AIDP的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a8/7872614/a5d5d835f237/cpcem-05-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a8/7872614/a5d5d835f237/cpcem-05-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a8/7872614/a5d5d835f237/cpcem-05-113-g001.jpg

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