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体检发现两例表现罕见的嗜酸性粒细胞性胃肠炎病例。

Two Cases of Eosinophilic Gastroenteritis With Rare Manifestations Revealed in Medical Checkup Findings.

作者信息

Mishiro Tsuyoshi, Nagase Mamiko, Nagasaki Makoto, Adachi Kyoichi, Ishihara Shunji

机构信息

Department of Gastroenterology and Hepatology, Faculty of Medicine, Shimane University, Izumo, JPN.

Department of Organ Pathology, Shimane University School of Medicine, Izumo, JPN.

出版信息

Cureus. 2020 Dec 17;12(12):e12118. doi: 10.7759/cureus.12118.

DOI:10.7759/cureus.12118
PMID:33489532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7808960/
Abstract

Eosinophilic gastroenteritis (EGE) is characterized by dense infiltration of eosinophils in gastrointestinal tissues, resulting in morphological and functional abnormalities of the gastrointestinal tract. EGE susceptibility is most common among individuals aged 40-50 years old, and hence it is likely that affected patients will be encountered at the time of a medical checkup. In this report, we present two rare cases of EGE that presented interesting manifestations in findings obtained in a fluoroscopic examination performed at an annual medical checkup. Accumulation of case reports is important to provide information to pathologists to enable them to make correct early diagnosis and begin effective treatment at the earliest.

摘要

嗜酸性粒细胞性胃肠炎(EGE)的特征是胃肠道组织中嗜酸性粒细胞密集浸润,导致胃肠道形态和功能异常。EGE易感性在40至50岁的个体中最为常见,因此在体检时可能会遇到受影响的患者。在本报告中,我们展示了两例罕见的EGE病例,它们在年度体检时进行的荧光检查结果中呈现出有趣的表现。积累病例报告对于向病理学家提供信息非常重要,以便他们能够做出正确的早期诊断并尽早开始有效治疗。

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Two Cases of Eosinophilic Gastroenteritis With Rare Manifestations Revealed in Medical Checkup Findings.体检发现两例表现罕见的嗜酸性粒细胞性胃肠炎病例。
Cureus. 2020 Dec 17;12(12):e12118. doi: 10.7759/cureus.12118.
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本文引用的文献

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Serum Biomarkers for the Diagnosis of Eosinophilic Esophagitis and Eosinophilic Gastroenteritis.用于诊断嗜酸性食管炎和嗜酸性胃肠炎的血清生物标志物。
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Eosinophilic gastroenteritis: an unusual type of gastroenteritis.
嗜酸性粒细胞性胃肠炎:一种不常见的胃肠炎类型。
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Limited role of allergy testing in patients with eosinophilic gastrointestinal disorders.变应原检测在嗜酸性粒细胞性胃肠道疾病患者中的作用有限。
J Gastroenterol Hepatol. 2013 Aug;28(8):1306-13. doi: 10.1111/jgh.12197.
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Eosinophilic gastrointestinal disease and peanut allergy are alternatively associated with IL-5+ and IL-5(-) T(H)2 responses.嗜酸粒细胞性胃肠道疾病和花生过敏与 IL-5+ 和 IL-5(-) T(H)2 反应交替相关。
J Allergy Clin Immunol. 2009 Dec;124(6):1326-32.e6. doi: 10.1016/j.jaci.2009.09.048.
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Eosinophilic gastroenteritis.嗜酸性胃肠炎
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Eosinophilic gastrointestinal disorders (EGID).嗜酸性胃肠道疾病(EGID)。
J Allergy Clin Immunol. 2004 Jan;113(1):11-28; quiz 29. doi: 10.1016/j.jaci.2003.10.047.
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Eosinophilic gastroenteritis: clinical experience with 15 patients.嗜酸性胃肠炎:15例患者的临床经验
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A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy.嗜酸性粒细胞趋化因子在实验性口服抗原诱导的嗜酸性粒细胞性胃肠过敏中的关键作用。
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Eosinophilic gastroenteritis.嗜酸性胃肠炎
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