Dhir Abhishek, Kaur Baldeep, Syal Arshi, Gupta Monica, Mehdi Zainab
General Medicine, Government Medical College and Hospital, Chandigarh, IND.
Medicine, Government Medical College and Hospital, Chandigarh, IND.
Cureus. 2020 Dec 17;12(12):e12119. doi: 10.7759/cureus.12119.
Methyl ethyl ketone peroxide (MEKP) is a colorless-to-faintly-yellow liquid that is used as a cross-linking to harden plastics or resins in various industries. It is also an ingredient of paints, varnishes, and paint removers. Because of the high reactivity of MEKP, it is available only as a 40% to 60% solution in dimethyl phthalate or other phthalates. Post-ingestion, the spectrum of complications is vast, ranging from corrosive injury in the oral cavity and gastrointestinal tract to fulminant hepatic toxicity, sepsis, multi-organ failure, and disseminated intravascular coagulation. We report the case of a 40-year-old, self-employed, male worker in a lamination workshop, who presented with accidental ingestion of MEKP from an unlabeled container. He subsequently developed a multitude of complications, most noteworthy being rhabdomyolysis and in turn acute kidney injury. The patient was managed in the intensive care unit with supportive management and hemodialysis sessions; however, the patient succumbed to his illness, despite aggressive measures.
过氧化甲乙酮（MEKP）是一种无色至淡黄色的液体，在各个行业中用作交联剂以硬化塑料或树脂。它也是油漆、清漆和脱漆剂的成分之一。由于MEKP具有高反应活性，它仅以在邻苯二甲酸二甲酯或其他邻苯二甲酸盐中的40%至60%溶液形式存在。摄入后，并发症范围广泛，从口腔和胃肠道的腐蚀性损伤到暴发性肝毒性、败血症、多器官衰竭和弥散性血管内凝血。我们报告了一名40岁的个体经营男性工人的病例，他在层压车间工作时意外从一个未贴标签的容器中摄入了MEKP。随后他出现了多种并发症，最值得注意的是横纹肌溶解症，进而导致急性肾损伤。该患者在重症监护病房接受了支持性治疗和血液透析；然而，尽管采取了积极措施，患者仍因病死亡。
