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保加利亚宫颈癌流行病学与预防概述。

An overview of cervical cancer epidemiology and prevention in Bulgaria.

作者信息

Karcheva Milena, Yordanov Angel, Kostadinov Sergey

机构信息

MD, PhD, Assoc. Prof., Department of Epidemiology, Faculty of Public Health, Medical University-Pleven, Pleven, 5800, Bulgaria.

MD, PhD, Chief Assis. Prof., Department of Midwifery, Faculty of Health Care, Medical University-Pleven, Pleven, 5800, Bulgaria.

出版信息

Germs. 2020 Dec 28;10(4):322-327. doi: 10.18683/germs.2020.1224. eCollection 2020 Dec.

Abstract

INTRODUCTION

Cervical cancer ranks as the fourth leading cause of female cancer in Bulgaria. The objective of the study was to describe the current burden of cervical cancer in Bulgaria for a one-year period and prevention options.

METHODS

In this retrospective epidemiological study, online database from National Statistical Institute-Sofia, National Center of Public Health and Analyses-Sofia, National Center of Infectious and Parasitic Diseases-Sofia for one year were analyzed. Annual data were presented in numbers and per 100 000 of population.

RESULTS

A total of 15,759 women in Bulgaria were diagnosed with cervical cancer in 2018. Morbidity is 23.5 of 100 000 population. Mortality of malignancy of the cervix in 2018 per 100 000 populations was 8.4 among women. Differences of mortality have been recorded as per statistical regions. A low immunization range has been recorded of vaccine against human papilloma virus (HPV) - 7.2% (girls 13 years of age) and 12.8% (girls 12 years of age) for first dose and 11.9% (girls 12 year of age) for second dose in 2019.

CONCLUSIONS

High morbidity and mortality from cervical cancer were registered in Bulgaria. The immunization coverage was low. The strategy for disease prevention through mandatory screening and mandatory immunizations needs to be rethought.

摘要

引言

在保加利亚,宫颈癌是女性癌症的第四大主要病因。本研究的目的是描述保加利亚一年内宫颈癌的当前负担以及预防措施。

方法

在这项回顾性流行病学研究中,对来自索非亚国家统计局、索非亚国家公共卫生与分析中心、索非亚国家传染病与寄生虫病中心的一年期在线数据库进行了分析。年度数据以数字形式呈现,并按每10万人口计算。

结果

2018年保加利亚共有15759名女性被诊断出患有宫颈癌。发病率为每10万人口23.5例。2018年每10万人口中宫颈癌恶性肿瘤的女性死亡率为8.4例。按统计区域记录了死亡率差异。2019年,人乳头瘤病毒(HPV)疫苗的接种率较低——首剂接种率为7.2%(13岁女孩)和12.8%(12岁女孩),第二剂接种率为11.9%(12岁女孩)。

结论

保加利亚宫颈癌的发病率和死亡率较高。免疫接种覆盖率较低。需要重新思考通过强制筛查和强制免疫进行疾病预防的策略。

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An overview of cervical cancer epidemiology and prevention in Bulgaria.保加利亚宫颈癌流行病学与预防概述。
Germs. 2020 Dec 28;10(4):322-327. doi: 10.18683/germs.2020.1224. eCollection 2020 Dec.
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