• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

保加利亚宫颈癌流行病学与预防概述。

An overview of cervical cancer epidemiology and prevention in Bulgaria.

作者信息

Karcheva Milena, Yordanov Angel, Kostadinov Sergey

机构信息

MD, PhD, Assoc. Prof., Department of Epidemiology, Faculty of Public Health, Medical University-Pleven, Pleven, 5800, Bulgaria.

MD, PhD, Chief Assis. Prof., Department of Midwifery, Faculty of Health Care, Medical University-Pleven, Pleven, 5800, Bulgaria.

出版信息

Germs. 2020 Dec 28;10(4):322-327. doi: 10.18683/germs.2020.1224. eCollection 2020 Dec.

DOI:10.18683/germs.2020.1224
PMID:33489947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7811861/
Abstract

INTRODUCTION

Cervical cancer ranks as the fourth leading cause of female cancer in Bulgaria. The objective of the study was to describe the current burden of cervical cancer in Bulgaria for a one-year period and prevention options.

METHODS

In this retrospective epidemiological study, online database from National Statistical Institute-Sofia, National Center of Public Health and Analyses-Sofia, National Center of Infectious and Parasitic Diseases-Sofia for one year were analyzed. Annual data were presented in numbers and per 100 000 of population.

RESULTS

A total of 15,759 women in Bulgaria were diagnosed with cervical cancer in 2018. Morbidity is 23.5 of 100 000 population. Mortality of malignancy of the cervix in 2018 per 100 000 populations was 8.4 among women. Differences of mortality have been recorded as per statistical regions. A low immunization range has been recorded of vaccine against human papilloma virus (HPV) - 7.2% (girls 13 years of age) and 12.8% (girls 12 years of age) for first dose and 11.9% (girls 12 year of age) for second dose in 2019.

CONCLUSIONS

High morbidity and mortality from cervical cancer were registered in Bulgaria. The immunization coverage was low. The strategy for disease prevention through mandatory screening and mandatory immunizations needs to be rethought.

摘要

引言

在保加利亚,宫颈癌是女性癌症的第四大主要病因。本研究的目的是描述保加利亚一年内宫颈癌的当前负担以及预防措施。

方法

在这项回顾性流行病学研究中,对来自索非亚国家统计局、索非亚国家公共卫生与分析中心、索非亚国家传染病与寄生虫病中心的一年期在线数据库进行了分析。年度数据以数字形式呈现,并按每10万人口计算。

结果

2018年保加利亚共有15759名女性被诊断出患有宫颈癌。发病率为每10万人口23.5例。2018年每10万人口中宫颈癌恶性肿瘤的女性死亡率为8.4例。按统计区域记录了死亡率差异。2019年,人乳头瘤病毒(HPV)疫苗的接种率较低——首剂接种率为7.2%(13岁女孩)和12.8%(12岁女孩),第二剂接种率为11.9%(12岁女孩)。

结论

保加利亚宫颈癌的发病率和死亡率较高。免疫接种覆盖率较低。需要重新思考通过强制筛查和强制免疫进行疾病预防的策略。

相似文献

1
An overview of cervical cancer epidemiology and prevention in Bulgaria.保加利亚宫颈癌流行病学与预防概述。
Germs. 2020 Dec 28;10(4):322-327. doi: 10.18683/germs.2020.1224. eCollection 2020 Dec.
2
The projected timeframe until cervical cancer elimination in Australia: a modelling study.澳大利亚消除宫颈癌的预计时间框架:建模研究。
Lancet Public Health. 2019 Jan;4(1):e19-e27. doi: 10.1016/S2468-2667(18)30183-X. Epub 2018 Oct 2.
3
Cost-effectiveness analysis of a quadrivalent human papilloma virus vaccine in Mexico.四价人乳头瘤病毒疫苗在墨西哥的成本效益分析。
Arch Med Res. 2009 Aug;40(6):503-13. doi: 10.1016/j.arcmed.2009.08.004.
4
Implementation of a human papillomavirus vaccination demonstration project in Malawi: successes and challenges.在马拉维实施人乳头瘤病毒疫苗示范项目:成功经验与挑战
BMC Public Health. 2017 Jun 26;17(1):599. doi: 10.1186/s12889-017-4526-y.
5
Economic evaluation of policy options for prevention and control of cervical cancer in Thailand.泰国宫颈癌预防和控制政策选择的经济评价。
Pharmacoeconomics. 2011 Sep;29(9):781-806. doi: 10.2165/11586560-000000000-00000.
6
[Prevention of cervical cancer (II): prophylactic HPV vaccination, current knowledge, practical procedures and new issues].[宫颈癌的预防(二):预防性人乳头瘤病毒疫苗、现有知识、实际操作及新问题]
Presse Med. 2007 Apr;36(4 Pt 2):640-66. doi: 10.1016/j.lpm.2007.02.004. Epub 2007 Mar 12.
7
Public health impact and cost effectiveness of routine and catch-up vaccination of girls and women with a nine-valent HPV vaccine in Japan: a model-based study.在日本,九价 HPV 疫苗对女童和妇女进行常规和补种接种的公共卫生影响和成本效益:基于模型的研究。
BMC Infect Dis. 2021 Jan 6;21(1):11. doi: 10.1186/s12879-020-05632-0.
8
Thyroid Cancer Incidence in Bulgaria before and after the Introduction of Universal Salt Iodization: An Analysis of the National Cancer Registry Data.保加利亚全民食盐碘化前后甲状腺癌发病率的变化:国家癌症登记数据分析。
Balkan Med J. 2020 Oct 23;37(6):330-335. doi: 10.4274/balkanmedj.galenos.2020.2019.10.5. Epub 2020 Aug 28.
9
Epidemiology and cost of cervical cancer care and prevention in Apulia (Italy), 2007/2016.2007/2016年意大利普利亚地区宫颈癌护理与预防的流行病学及成本
Ann Ig. 2018 Nov-Dec;30(6):490-501. doi: 10.7416/ai.2018.2249.
10

引用本文的文献

1
Relative Risk of Death in Bulgarian Cancer Patients during the Initial Waves of the COVID-19 Pandemic.保加利亚癌症患者在新冠疫情最初几波期间的死亡相对风险
Healthcare (Basel). 2023 Sep 20;11(18):2594. doi: 10.3390/healthcare11182594.
2
Economic Burden of Cervical Cancer in Bulgaria.保加利亚宫颈癌的经济负担。
Int J Environ Res Public Health. 2023 Feb 3;20(3):2746. doi: 10.3390/ijerph20032746.

本文引用的文献

1
Cervical cancer and vaginal microbiota changes.宫颈癌与阴道微生物组变化。
Arch Microbiol. 2020 Mar;202(2):323-327. doi: 10.1007/s00203-019-01747-4. Epub 2019 Oct 28.
2
Impact of cervical screening on cervical cancer mortality: estimation using stage-specific results from a nested case-control study.宫颈筛查对宫颈癌死亡率的影响:利用巢式病例对照研究的特定分期结果进行估计
Br J Cancer. 2016 Oct 25;115(9):1140-1146. doi: 10.1038/bjc.2016.290. Epub 2016 Sep 15.
3
Temporal changes in the cervical cancer burden in Bulgaria: Implications for eastern european countries going through transition.保加利亚宫颈癌负担的时间变化:对正在经历转型的东欧国家的启示。
Cancer Epidemiol. 2016 Oct;44:154-160. doi: 10.1016/j.canep.2016.08.014. Epub 2016 Sep 3.
4
Human papillomavirus and cervical cancer.人乳头瘤病毒与宫颈癌。
Lancet. 2013 Sep 7;382(9895):889-99. doi: 10.1016/S0140-6736(13)60022-7. Epub 2013 Apr 23.