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也门霍乱患者中的严重脱水:一项队列研究概况

Severe dehydration among cholera patients in Yemen: A cohort profile.

作者信息

Alassar Mohammed M, Adegboye Oyelola A, Emeto Theophilus I, Rahman Kazi M, Mashood Lawal Olumuyiwa, Elfaki Faiz Am

机构信息

MD, Faculty of Medicine, Taiz University, PO Box 6803, Taiz, Yemen.

PhD, Australian Institute of Tropical Health and Medicine, Discovery Drive, James Cook University, Townsville, QLD 4811, Australia.

出版信息

Germs. 2020 Dec 28;10(4):338-345. doi: 10.18683/germs.2020.1226. eCollection 2020 Dec.

Abstract

INTRODUCTION

Introduction Cholera, an acute diarrheal illness caused by ingestion of food or water contaminated with , is one of the major causes of morbidity and mortality globally. The occurrence of outbreaks of cholera are difficult to prevent in low and middle-income countries, especially those under armed conflicts.

METHODS

This study aimed to describe the characteristics of a cohort of inpatients with cholera in two main hospitals in Taiz and Sana'a, Yemen, between 3 February 2017 and 8 December 2017. Patient data were entered into an excel database and analyzed using STATA 16.1. Descriptive summaries of patient's data were presented as frequencies and percentages. Patients' demographic and clinical characteristics were compared using the Chi-square test.

RESULTS

Preliminary findings from 172 hospitalizations for cholera during the study period include 163 that were severely dehydrated (94.8%). Age, education, hand hygiene, sanitation, water source, stool content and malnutrition were significantly associated with severe dehydration.

CONCLUSIONS

This data contributes to a greater understanding of the associated risk factors for the occurrence of the infectious disease in the study region. Future study will analyze the risks for severe dehydration and diarrhea, and the associated healthcare costs.

摘要

引言

霍乱是一种因摄入被污染的食物或水而引发的急性腹泻疾病,是全球发病和死亡的主要原因之一。在低收入和中等收入国家,尤其是处于武装冲突中的国家,霍乱疫情的爆发难以预防。

方法

本研究旨在描述2017年2月3日至2017年12月8日期间也门塔伊兹和萨那两家主要医院霍乱住院患者队列的特征。将患者数据录入Excel数据库,并使用STATA 16.1进行分析。患者数据的描述性总结以频率和百分比形式呈现。使用卡方检验比较患者的人口统计学和临床特征。

结果

研究期间172例霍乱住院患者的初步结果显示,163例严重脱水(94.8%)。年龄、教育程度、手部卫生、环境卫生、水源、粪便成分和营养不良与严重脱水显著相关。

结论

这些数据有助于更深入了解研究区域内该传染病发生的相关风险因素。未来的研究将分析严重脱水和腹泻的风险以及相关的医疗费用。

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本文引用的文献

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Genomic insights into the 2016-2017 cholera epidemic in Yemen.对 2016-2017 年也门霍乱疫情的基因组学分析。
Nature. 2019 Jan;565(7738):230-233. doi: 10.1038/s41586-018-0818-3. Epub 2019 Jan 2.
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Cholera epidemic in Yemen, 2016-18: an analysis of surveillance data.2016-2018 年也门霍乱疫情:监测数据分析。
Lancet Glob Health. 2018 Jun;6(6):e680-e690. doi: 10.1016/S2214-109X(18)30230-4. Epub 2018 May 3.
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Yemen in a Time of Cholera: Current Situation and Challenges.也门霍乱时期:现状与挑战。
Am J Trop Med Hyg. 2018 Jun;98(6):1558-1562. doi: 10.4269/ajtmh.17-0811. Epub 2018 Mar 15.
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Cholera in Yemen - An Old Foe Rearing Its Ugly Head.也门的霍乱——一个老对手再度现身。
N Engl J Med. 2017 Nov 23;377(21):2005-2007. doi: 10.1056/NEJMp1712099. Epub 2017 Nov 1.

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