Ocular and cardiovascular response to topical carteolol 2% and timolol 0.5% in healthy volunteers.
作者信息
Brazier D J, Smith S E
机构信息
Department of Clinical Pharmacology, St Thomas's Hospital Medical School (UMDS), London.
出版信息
Br J Ophthalmol. 1988 Feb;72(2):101-3. doi: 10.1136/bjo.72.2.101.
Abstract
Ocular and cardiovascular effects of carteolol 2%, timolol 0.5%, and dummy eyedrops have been measured in a single dose double-blind crossover study in six healthy volunteers. Both drugs lowered intraocular pressure and reduced exercise-induced tachycardia. Neither produced a significant change in resting heart rate or blood pressure. The two agents appear comparable as regards ocular hypotensive and cardiovascular effects.
摘要
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1
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2
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3
Betaxolol in patients with glaucoma and asthma.
Am J Ophthalmol. 1986 May 15;101(5):531-4. doi: 10.1016/0002-9394(86)90941-4.
4
A double-masked comparison of betaxolol vs timolol in the treatment of open-angle glaucoma.
Am J Ophthalmol. 1986 May 15;101(5):535-41. doi: 10.1016/0002-9394(86)90942-6.
5
A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study.
Br J Ophthalmol. 1986 Jan;70(1):39-42. doi: 10.1136/bjo.70.1.39.
6
Polymorphic hydroxylation of Debrisoquine in man.
Lancet. 1977 Sep 17;2(8038):584-6. doi: 10.1016/s0140-6736(77)91430-1.
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