越南一家医院急性胰腺炎患者抗生素使用情况调查。
Investigation of antibiotic use in patients with acute pancreatitis in a Vietnamese hospital.
作者信息
Thong Vo Duy, Anh Trinh Thi Hong, Quynh Bui Thi Huong, Quyt Ngo Thi Thanh
机构信息
Department of Internal Medicine Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh city Ho Chi Minh City Vietnam.
Department of Gastroenterology Cho Ray Hospital Ho Chi Minh City Vietnam.
出版信息
JGH Open. 2020 Dec 2;5(1):128-132. doi: 10.1002/jgh3.12461. eCollection 2021 Jan.
BACKGROUND AND AIM
The aim of this study was to investigate the antibiotics used in patients with acute pancreatitis and evaluate their appropriateness.
METHODS
We conducted a descriptive cross-sectional study on 136 patients aged 18 years or older who were diagnosed with acute pancreatitis and admitted to a national hospital in Ho Chi Minh City from January 2017 to December 2018. Medical records of patients were reviewed for data analysis, including epidemiological characteristics, pathological characteristics, treatment methods, and treatment effectiveness.
RESULTS
There were 69.9% men and 30.1% women with a median age of 49.9 years. The most common etiologies included alcohol (21.3%), gallstones (23.6%), and hypertriglyceridemia (19.9%). The proportions of mild, moderate, and severe disease were 54.4, 39.0, and 6.6%, respectively. Antibiotics were given in 52.2% of patients. Although antibiotic prophylaxis was not recommended, 23.5% of cases used prophylactic antibiotics when there were no suspicion or evidence of infection.
CONCLUSIONS
Our study suggests that it is necessary to optimize the appropriateness of antibiotic indications for patients with acute pancreatitis.
背景与目的
本研究旨在调查急性胰腺炎患者使用的抗生素并评估其合理性。
方法
我们对2017年1月至2018年12月期间在胡志明市一家国立医院确诊为急性胰腺炎并入院的136名18岁及以上患者进行了描述性横断面研究。查阅患者的病历以进行数据分析，包括流行病学特征、病理特征、治疗方法和治疗效果。
结果
男性占69.9%，女性占30.1%，中位年龄为49.9岁。最常见的病因包括酒精（21.3%）、胆结石（23.6%）和高甘油三酯血症（19.9%）。轻症、中症和重症的比例分别为54.4%、39.0%和6.6%。52.2%的患者使用了抗生素。尽管不建议预防性使用抗生素，但在没有感染怀疑或证据的情况下，23.5%的病例使用了预防性抗生素。
结论
我们的研究表明，有必要优化急性胰腺炎患者抗生素使用指征的合理性。
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