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肝移植术后血液透析患者的股骨颈骨折:一例报告

Femoral Neck Fracture in a Hemodialysis Patient after Liver Transplantation: A Case Report.

作者信息

Kamada Satoshi, Kise Naoki, Kinoshita Koichi, Shiota Etsuji, Yamamoto Takuaki

机构信息

Department of Rehabilitation Medicine, Fukuoka University Hospital, Fukuoka, Japan.

Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, Fukuoka, Japan.

出版信息

Prog Rehabil Med. 2021 Jan 22;6:20210003. doi: 10.2490/prm.20210003. eCollection 2021.

Abstract

BACKGROUND

Surgical treatment of femoral neck fractures is usually performed as an urgent procedure so that restoration of the ability to stand and walk can be achieved as quickly as possible. However, orthopedic surgeons need to be aware of undertreated or untreated diseases in their patients. Organ transplant recipients require immunosuppressive agents and steroids postoperatively. Hemodialysis patients also exhibit immunological deterioration and are included among immunocompromised patients. We report a case in which conservative treatment was chosen for a hepatic transplant recipient on hemodialysis who suffered a femoral neck fracture because signs of inflammation of unknown etiology were intermittently seen.

CASE

The patient was a 70-year-old man who had undergone liver transplantation from a living donor as treatment for hepatocellular cancer and hepatic failure with cirrhosis. Dialysis for end-stage renal failure was initiated at approximately 1 year postoperatively. Cyclosporine was administered as an immunosuppressive agent. The patient subsequently fell off a bicycle and was unable to walk because of right hip pain. He was brought to our hospital by ambulance, and a right hip radiograph revealed a femoral neck fracture. His white blood cell count and C-reactive protein levels were intermittently elevated with unknown etiology. Conservative treatment was finally adopted, although a bipolar hip arthroplasty was planned. At 5 months after the injury, the patient was able to walk alone in a stable manner using a pair of crutches and was discharged.

DISCUSSION

Conservative treatment for a femoral neck fracture, which generally requires surgery, may be acceptable in organ transplant recipients on hemodialysis.

摘要

背景

股骨颈骨折的外科治疗通常作为紧急手术进行,以便尽快恢复站立和行走能力。然而,骨科医生需要注意患者中未得到充分治疗或未治疗的疾病。器官移植受者术后需要使用免疫抑制剂和类固醇。血液透析患者也表现出免疫功能恶化,属于免疫功能低下患者。我们报告一例因间歇性出现病因不明的炎症迹象而选择保守治疗的接受血液透析的肝移植受者股骨颈骨折病例。

病例

患者为一名70岁男性,因肝细胞癌和肝硬化伴肝衰竭接受了活体供体肝移植。术后约1年开始进行终末期肾衰竭透析。给予环孢素作为免疫抑制剂。患者随后从自行车上摔下,因右髋疼痛无法行走。他被救护车送往我院,右髋部X线片显示股骨颈骨折。其白细胞计数和C反应蛋白水平间歇性升高,病因不明。尽管计划进行双极髋关节置换术,但最终还是采用了保守治疗。受伤5个月后,患者能够使用双拐稳定地独自行走并出院。

讨论

对于股骨颈骨折通常需要手术治疗,但在接受血液透析的器官移植受者中,保守治疗可能是可以接受的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e8f/7817843/56f8334e98a6/prm-6-20210003-g001.jpg

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