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在2019冠状病毒病大流行初期激增期间,ICU危机重组对未感染2019冠状病毒病患者预后的影响。

The Effects of ICU Crisis Reorganization on Outcomes in Patients Not Infected With Coronavirus Disease 2019 During the Initial Surge of the Coronavirus Disease 2019 Pandemic.

作者信息

Rana Sameer, Hughes Laura A, Rana Siddharth, Adam Laura A

机构信息

Department of Critical Care Medicine, Mercy Hospital South, St. Louis, MO.

出版信息

Crit Care Explor. 2021 Jan 13;3(1):e0333. doi: 10.1097/CCE.0000000000000333. eCollection 2021 Jan.

Abstract

UNLABELLED

To determine if ICU reorganization due to the coronavirus disease 2019 pandemic affected outcomes in critically ill patients who were not infected with coronavirus disease 2019.

DESIGN

This was a Before-After study, with coronavirus disease 2019-induced ICU reorganization as the intervention. A retrospective chart review of adult patients admitted to a reorganized ICU during the coronavirus disease 2019 surge (from March 23, 2020, to May 06, 2020: intervention group) was compared with patients admitted to the ICU prior to coronavirus disease 2019 surge (from January 10, 2020, to February 23, 2020: before group).

SETTING

High-intensity cardiac, medical, and surgical ICUs of a community hospital in metropolitan Missouri.

PATIENTS

All patients admitted to the ICU during the before and intervention period were included. Patients younger than 18 years old and those admitted after an elective procedure or surgery were excluded. Patients with coronavirus disease 2019 were excluded.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

We identified a total of 524 eligible patients: 342 patients in the before group and 182 in the intervention group. The 28-day mortality was 25.1% (86/342) and 28.6% (52/182), respectively ( = 0.40). The ICU length of stay, ventilator length of stay, and ventilator-free days were similar in both groups. Rates of patient adverse events including falls, inadvertent endotracheal tube removal, reintubation within 48 hours of extubation, and hospital acquired pressure ulcers occurred more frequently in the study group (20 events, 11%) versus control group (12 events, 3.5%) ( = 0.001).

CONCLUSIONS

Twenty-eight-day mortality, in patients who required ICU care and were not infected with coronavirus disease 2019, was not significantly affected by ICU reorganization during a pandemic.

摘要

未标注

确定因2019冠状病毒病大流行导致的重症监护病房(ICU)重组是否会影响未感染2019冠状病毒病的重症患者的预后。

设计

这是一项前后对照研究,将2019冠状病毒病导致的ICU重组作为干预措施。对在2019冠状病毒病激增期间(2020年3月23日至2020年5月6日:干预组)入住重组ICU的成年患者进行回顾性病历审查,并与在2019冠状病毒病激增之前(2020年1月10日至2020年2月23日:前组)入住ICU的患者进行比较。

地点

密苏里州大都市一家社区医院的高强度心脏、内科和外科ICU。

患者

纳入在前后两个时期入住ICU的所有患者。排除年龄小于18岁的患者以及择期手术或手术后入院的患者。排除感染2019冠状病毒病的患者。

干预措施

无。

测量指标及主要结果

我们共确定了524例符合条件的患者:前组342例患者,干预组182例患者。28天死亡率分别为25.1%(86/342)和28.6%(52/182)(P = 0.40)。两组的ICU住院时间、呼吸机使用时间和无呼吸机天数相似。研究组(20起事件,11%)患者不良事件发生率,包括跌倒、意外拔管、拔管后48小时内再次插管和医院获得性压疮,高于对照组(12起事件,3.5%)(P = 0.001)。

结论

在大流行期间,需要ICU护理且未感染2019冠状病毒病的患者,其28天死亡率未受到ICU重组的显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3649/7808566/36c526d59166/cc9-3-e0333-g001.jpg

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