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在2019冠状病毒病大流行期间改善患者安全的干预措施:一项系统综述。

Interventions to improve patient safety during the COVID-19 pandemic: a systematic review.

作者信息

Wu Albert W, Trigg Katelyn, Zhang Allen, Alexander G Caleb, Haut Elliott R, Rock Clare, McDonald Kathryn, Padula William, Fisseha Sarah, Duncan Rosemary, Black Joyce, Newman-Toker David E, Papieva Irina, Dhingra-Kumar Neelam, Wilson Renee F

机构信息

Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA

Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.

出版信息

BMJ Open Qual. 2025 Jun 30;14(2):e003076. doi: 10.1136/bmjoq-2024-003076.

Abstract

OBJECTIVE

To summarise the literature on healthcare interventions to reduce harm to patients caused by the COVID-19 pandemic across six domains: medication safety, diagnostic safety, surgical safety, healthcare-associated infections, pressure injuries and falls.

METHODS

We performed a mixed-methods systematic review, with the intention to present results narratively. We combined parallel searches and expert input across each domain of interest, identifying 13 019 unique articles across the six domains. Of these, 590 full texts were assessed for eligibility. 7 were included for the medication safety domain; 7 for diagnostic safety; 32 for surgical safety; 11 for healthcare-associated infections; 5 for the pressure injuries and 2 for falls. Overall, a total of 61 unique articles were included-4 articles were represented across more than one domain.

FINDINGS

There were few rigorous evaluations of specific interventions to reduce patient harm caused by the pandemic. Adjustments in treatments, triage and procedures, and use of risk stratification tools reduced delays and permitted more elective surgery and diagnostic testing to proceed. These changes also led to improvements in medication safety practices and prevention of healthcare-associated infections.

CONCLUSION

There has been little research on interventions to reduce patient harm caused in healthcare settings during the COVID-19 pandemic. Interventions focused on preventing nosocomial transmission of COVID-19 and on permitting access to urgent surgical and diagnostic needs. A few studies tested strategies to reduce new risks imposed by the pandemic for medication safety, healthcare-associated infections, pressure injuries and falls. Development of high-reliability health systems and healthcare organisations to protect patients and health workers from harm will be essential to mitigating the impact of future pandemics within the objectives of the Global Patient Safety Action Plan 2021-2030.

摘要

目的

总结关于医疗保健干预措施的文献,这些措施旨在减少2019年冠状病毒病(COVID-19)大流行在六个领域对患者造成的伤害:用药安全、诊断安全、手术安全、医疗保健相关感染、压疮和跌倒。

方法

我们进行了一项混合方法的系统评价,旨在以叙述方式呈现结果。我们结合了对每个感兴趣领域的平行检索和专家意见,在六个领域共识别出13019篇独特的文章。其中,590篇全文被评估是否符合纳入标准。用药安全领域纳入7篇;诊断安全领域纳入7篇;手术安全领域纳入32篇;医疗保健相关感染领域纳入11篇;压疮领域纳入5篇;跌倒领域纳入2篇。总体而言,共纳入61篇独特的文章,有4篇文章涉及多个领域。

研究结果

针对减少大流行对患者造成伤害的具体干预措施,严格评估较少。治疗、分诊和程序的调整,以及风险分层工具的使用减少了延误,并使更多择期手术和诊断检测得以进行。这些变化还改善了用药安全实践,并预防了医疗保健相关感染。

结论

关于减少COVID-19大流行期间医疗环境中对患者造成伤害的干预措施的研究很少。干预措施侧重于预防COVID-19的医院内传播,并满足紧急手术和诊断需求。一些研究测试了减少大流行给用药安全、医疗保健相关感染、压疮和跌倒带来新风险的策略。发展高可靠性的卫生系统和医疗保健组织以保护患者和医护人员免受伤害,对于在《2021-2030年全球患者安全行动计划》目标范围内减轻未来大流行的影响至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2337/12211853/d0de76835fa3/bmjoq-14-2-g001.jpg

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