Spitkovskiĭ D D, Revazova E S
Biull Eksp Biol Med. 1988 Mar;105(3):326-9.
Expression of 3 cellular oncogenes among 7 ones under investigation is identified in the majority of 20 strains of human tumors, passaged in nude mice without significant specificity as far as the type of the tumor is concerned. The levels of the expression of these 3 oncogenes (c-myc, c-fos, c-ras) were higher than the ones in primary human tumors except for the human melanoma Mel-2 strain, where the expression of c-myb oncogene was identified. All the rest oncogenes (c-mos, B-lym, c-sis, c-myb) showed no expression in human tumors of the examined strains.
在所研究的7种细胞癌基因中，3种癌基因的表达在20株人肿瘤裸鼠传代瘤中多数被检测到，就肿瘤类型而言无明显特异性。除人黑色素瘤Mel-2株检测到c-myb癌基因表达外，这3种癌基因（c-myc、c-fos、c-ras）的表达水平均高于原发性人肿瘤中的表达水平。其余所有癌基因（c-mos、B-lym、c-sis、c-myb）在所检测的人肿瘤株中均未表达。
