Kudriavets Iu I, Kiseleva N P, Asanova A A, Pinchuk V G
Biull Eksp Biol Med. 1988 Jul;106(7):86-8.
The expression of 8 oncogenes in transplanted rodent tumours and cell lines was tested. In 6 cases the synthesis of myc-, fos-, ras-oncogene RNA was observed. The transcription of these oncogenes was observed nonspecifically in tumours of different histological types. No difference in the set of the oncogenes expressed and the size of their transcripts was noticed between transplanted tumours and the cell lines obtained from them. The expression of myb-, sis-, Blym-, erb-B- and abl-was not observed in tested cells.
对移植的啮齿动物肿瘤和细胞系中8种癌基因的表达进行了检测。在6个病例中观察到了myc、fos、ras癌基因RNA的合成。这些癌基因的转录在不同组织学类型的肿瘤中均有非特异性观察到。在移植肿瘤与其衍生的细胞系之间,未发现所表达的癌基因组合及其转录本大小存在差异。在所检测的细胞中未观察到myb、sis、Blym、erb - B和abl的表达。