REQUIMTE/LAQV, Polytechnic of Porto - School of Engineering, Rua Dr. António Bernardino de Almeida, 4249-015, Porto, Portugal.
Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo, 5, 35121, Padova, Italy.
Chem Biodivers. 2021 Mar;18(3):e2000925. doi: 10.1002/cbdv.202000925. Epub 2021 Feb 10.
Hardy kiwifruit (Actinidia arguta) is a highly appreciated exotic fruit endowed with outstanding bioactive compounds. The present work proposes to characterize the pulp from A. arguta organic fruits, emphasizing its radicals scavenging capacity and effects on intestinal cells (Caco-2 and HT29-MTX). The physicochemical properties and phenolic profile were also screened. The total phenolic and flavonoid contents (TPC and TFC, respectively) of pulp were 12.21 mg GAE/g on dry weight (DW) and 5.92 mg CE/g DW, respectively. A high antioxidant activity was observed (FRAP: 151.41 μmol FSE/g DW; DPPH: 12.17 mg TE/g DW). Furthermore, the pulp did not induce a toxic effect on Caco-2 and HT29-MTX cells viability up to 1000 μg/mL. Regarding in vitro scavenging capacity, the pulp revealed the highest scavenging power against NO (IC =3.45 μg/mL) and HOCl (IC =12.77 μg/mL). These results emphasize the richness of A. arguta fruit pulp to be used in different food products.
海沃德猕猴桃(Actinidia arguta)是一种深受赞赏的外来水果,具有出色的生物活性化合物。本研究旨在对 A. arguta 有机果实的果肉进行特性描述,重点强调其自由基清除能力及其对肠道细胞(Caco-2 和 HT29-MTX)的影响。同时还对其物理化学性质和酚类成分进行了筛选。果肉的总酚和总黄酮含量(TPC 和 TFC,分别)分别为 12.21 mg GAE/g DW 和 5.92 mg CE/g DW。观察到具有高抗氧化活性(FRAP:151.41 μmol FSE/g DW;DPPH:12.17 mg TE/g DW)。此外,果肉在 1000 μg/mL 时对 Caco-2 和 HT29-MTX 细胞活力没有毒性作用。关于体外清除能力,果肉对 NO(IC =3.45 μg/mL)和 HOCl(IC =12.77 μg/mL)显示出最高的清除能力。这些结果强调了 A. arguta 果肉的丰富性,可用于不同的食品产品。