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Interactions of the imidazodiazepine Ro 15-4513 with chemical convulsants.
Br J Pharmacol. 1988 Jan;93(1):210-4. doi: 10.1111/j.1476-5381.1988.tb11423.x.
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Antagonizing the anticonvulsant effect of ethanol using drugs acting at the benzodiazepine/GABA receptor complex.
Pharmacol Biochem Behav. 1988 Nov;31(3):751-5. doi: 10.1016/0091-3057(88)90260-2.
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Investigating benzodiazepine receptor function in vivo using an intravenous infusion of DMCM.
Eur J Pharmacol. 1984 Aug 17;103(3-4):359-62. doi: 10.1016/0014-2999(84)90500-4.
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Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
Eur J Pharmacol. 1989 Jan 17;159(3):233-9. doi: 10.1016/0014-2999(89)90153-2.
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DMCM: a potent convulsive benzodiazepine receptor ligand.
Eur J Pharmacol. 1983 Oct 14;94(1-2):117-24. doi: 10.1016/0014-2999(83)90448-x.
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Pro- and anti-convulsant drug effects in combination with the convulsant benzodiazepine Ro 5-4864.
J Pharm Pharmacol. 1985 Aug;37(8):560-3. doi: 10.1111/j.2042-7158.1985.tb03067.x.
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The benzodiazepine receptor ligand, methyl beta-carboline-3-carboxylate, is both sedative and proconvulsant in chicks.
Life Sci. 1986 Sep 22;39(12):1093-100. doi: 10.1016/0024-3205(86)90201-8.
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Discriminative stimulus properties of methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM), an inverse agonist at benzodiazepine receptors.
Life Sci. 1985 Jan 7;36(1):15-23. doi: 10.1016/0024-3205(85)90281-4.
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Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists.
Neuropharmacology. 2002 Sep;43(4):679-84. doi: 10.1016/s0028-3908(02)00159-4.
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A proconvulsant action of selective alpha 2-adrenoceptor antagonists.
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引用本文的文献
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Αlpha 5 subunit-containing GABA receptors in temporal lobe epilepsy with normal MRI.
Brain Commun. 2021 Jan 7;3(1):fcaa190. doi: 10.1093/braincomms/fcaa190. eCollection 2021.
2
Test-retest reproducibility of quantitative binding measures of [C]Ro15-4513, a PET ligand for GABA receptors containing alpha5 subunits.
Neuroimage. 2017 May 15;152:270-282. doi: 10.1016/j.neuroimage.2016.12.038. Epub 2017 Mar 11.
3
Ethanol self-administration in freely feeding and drinking rats: effects of Ro15-4513 alone, and in combination with Ro15-1788 (flumazenil).
Psychopharmacology (Berl). 1994 Jul;115(3):332-9. doi: 10.1007/BF02245074.
4
The benzodiazepine inverse agonist RO19-4603 exerts prolonged and selective suppression of ethanol intake in alcohol-preferring (P) rats.
Psychopharmacology (Berl). 1994 Jul;115(3):325-31. doi: 10.1007/BF02245073.
5
Effects of ethanol and imidazobenzodiazepine Ro 15-4513 on spontaneous saccades of the pigmented rat.
Exp Brain Res. 1989;76(1):1-11. doi: 10.1007/BF00253617.
6
Ethanol and the benzodiazepine-GABA receptor-ionophore complex.
Experientia. 1989 May 15;45(5):413-8. doi: 10.1007/BF01952022.
7
Ethanol-induced locomotor stimulation in C57BL/6 mice following RO15-4513 administration.
Psychopharmacology (Berl). 1989;99(3):333-6. doi: 10.1007/BF00445553.
8
Convulsive thresholds in mice during the recovery phase from anaesthesia induced by propofol, thiopentone, methohexitone and etomidate.
Br J Pharmacol. 1991 Apr;102(4):879-82. doi: 10.1111/j.1476-5381.1991.tb12270.x.
本文引用的文献
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On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock.
Neuropharmacology. 1980 Oct;19(10):1017-23. doi: 10.1016/0028-3908(80)90014-3.
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Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
J Neurochem. 1984 Jan;42(1):221-9. doi: 10.1111/j.1471-4159.1984.tb09721.x.
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Antagonism of caffeine-induced seizures in mice by Ro15-1788.
Eur J Pharmacol. 1984 Jan 27;97(3-4):289-93. doi: 10.1016/0014-2999(84)90462-x.
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Pharmacokinetic studies on Ro 15-1788, a benzodiazepine receptor ligand, in the brain of the rat.
Brain Res. 1984 Jan 2;290(1):183-6. doi: 10.1016/0006-8993(84)90752-2.
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The picrotoxin-like action of a convulsant benzodiazepine, Ro5-3663.
Eur J Pharmacol. 1983 Jan 28;87(1):155-8. doi: 10.1016/0014-2999(83)90064-x.
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Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663.
Psychopharmacology (Berl). 1982;78(3):293-5. doi: 10.1007/BF00428169.
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Classification of some GABA antagonists with regard to site of action and potency in slices of rat cuneate nucleus.
Eur J Pharmacol. 1982 Jun 4;80(4):347-58. doi: 10.1016/0014-2999(82)90080-2.
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Adenosine receptors and behavioral actions of methylxanthines.
Proc Natl Acad Sci U S A. 1981 May;78(5):3260-4. doi: 10.1073/pnas.78.5.3260.
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GABA-benzodiazepine-barbiturate receptor interactions.
J Neurochem. 1981 Jul;37(1):1-13. doi: 10.1111/j.1471-4159.1981.tb05284.x.
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Studies on the post-ictal rise in seizure threshold.
Eur J Pharmacol. 1981 May 8;71(2-3):287-95. doi: 10.1016/0014-2999(81)90031-5.
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