Mousavi Movahed Seyed Majid, Akbarpour Samaneh, Saraei Maryam, Mahboobi Marzieh, Najafi Arezu, Taghizadadeh Fatemeh
Occupational Sleep Research Center (OSRC), Baharloo Hospital, Tehran University of Medical Sciences, Iran.
Iran J Kidney Dis. 2021 Jan;1(1):17-21.
Chronic Kidney Disease (CKD) is of high clinical importance due to cost of outcomes such as kidney transplantation. However, CKD is an overlooked disorder among commercial drivers. The present study aimed to evaluate hypertension and Glomerular Filtration Rate (GFR) among commercial drivers.
In this cross-sectional study, a total of 903 commercial drivers referred for obtaining their health license were recruited. After obtaining informed consent, a questionnaire consisted of demographic characteristics was completed. Blood pressure, level of lipid profile, blood sugar, blood urea nitrogen, and plasma creatinine were measured. Chi-square and independent T-test were used for data analysis.
All participants were male. The mean ( ± SD) age and Body mass index were 42 ± (10) years and 27 ± (4) kg/m2, respectively. Of 903 studied cases 40 (4%) had GFR < 60. Increased age and high blood pressure had a significant association with reduced GFR (P < .0001). The ones with sleep apnea were more likely to have GFR < 60, however, the association was not statistically significant after adjusting for related risk factors.
Older age and hypertension are considered as risk factors for CKD among commercial drivers. Obstructive sleep apnea also should be kept in mind as a possible risk factor that requires further elucidation and management.
由于诸如肾移植等治疗结果的成本，慢性肾脏病（CKD）具有很高的临床重要性。然而，CKD在商业司机中是一种被忽视的疾病。本研究旨在评估商业司机中的高血压和肾小球滤过率（GFR）。
在这项横断面研究中，共招募了903名前来获取健康许可证的商业司机。在获得知情同意后，完成了一份包含人口统计学特征的问卷。测量了血压、血脂水平、血糖、血尿素氮和血浆肌酐。使用卡方检验和独立样本t检验进行数据分析。
所有参与者均为男性。平均（±标准差）年龄和体重指数分别为42±（10）岁和27±（4）kg/m²。在903例研究病例中，40例（4%）的GFR<60。年龄增加和高血压与GFR降低有显著关联（P<.0001）。患有睡眠呼吸暂停的人更有可能GFR<60，然而，在调整相关风险因素后，这种关联没有统计学意义。
年龄较大和高血压被认为是商业司机中CKD的风险因素。阻塞性睡眠呼吸暂停也应被视为一个可能的风险因素，需要进一步阐明和管理。
