Nanthakumar Meenu Priyadarshini, Sood Akanksha, Ahmed Maimoona, Gupta Janesh
Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
St. Mary's Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Eur J Obstet Gynecol Reprod Biol. 2021 Mar;258:283-287. doi: 10.1016/j.ejogrb.2021.01.009. Epub 2021 Jan 12.
Chickenpox during pregnancy can cause serious complications for both mother and fetus. This includes varicella pneumonia in the mother, fetal varicella syndrome and varicella of newborn. Primary prevention includes vaccination against varicella infection and is part of standard childhood immunisation programme in many countries. Timely post-exposure prophylaxis of susceptible pregnant women with varicella zoster immunoglobulin is key to preventing chickenpox during pregnancy and its adverse fetomaternal sequelae. Antiviral therapy and appropriate supportive treatment improve maternal and neonatal outcomes.
孕期患水痘可对母亲和胎儿造成严重并发症。这包括母亲患水痘肺炎、胎儿水痘综合征和新生儿水痘。一级预防包括接种水痘疫苗，这是许多国家儿童标准免疫规划的一部分。对易感孕妇及时进行暴露后水痘带状疱疹免疫球蛋白预防是预防孕期水痘及其母婴不良后果的关键。抗病毒治疗和适当的支持性治疗可改善母婴结局。
