Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Task Force on Microbiome Studies, University of Naples Federico II, 80100 Naples, Italy.
Int J Environ Res Public Health. 2021 Jan 21;18(3):904. doi: 10.3390/ijerph18030904.
Coronaviruses (CoVs) represent a large family of RNA viruses that can infect different living species, posing a global threat to human health. CoVs can evade the immune response, replicate within the host, and cause a rapid immune compromise culminating in severe acute respiratory syndrome. In humans, the immune system functions are influenced by physical activity, nutrition, and the absence of respiratory or cardiovascular diseases. This review provides an in-depth study between the interactions of the immune system and coronaviruses in the host to defend against CoVs disease.
冠状病毒(CoVs)是一类能够感染不同生物的 RNA 病毒,对人类健康构成全球性威胁。CoVs 可以逃避免疫反应,在宿主内复制,并导致严重的急性呼吸综合征,使宿主的免疫功能迅速受损。在人类中,免疫系统的功能受到身体活动、营养和无呼吸道或心血管疾病的影响。本综述深入研究了宿主中免疫系统与冠状病毒之间的相互作用,以抵御 CoV 疾病。