Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Curr Stem Cell Res Ther. 2021;16(6):745-752. doi: 10.2174/1574888X16666210120101223.
The past decade has evidenced numerous developments in the treatment of heart diseases; however many patients with chronic heart failure suffer from low quality of life. Therapeutic methods, including drug-delivery as well as heart transplantation, have been used to improve quality of life. Cell therapy and tissue engineering have been recently introduced to the field of medicine as a novel therapeutic approach. Treatment of heart diseases has seen novel development through the introduction of cell therapy approaches. Based on the evidence, cell therapy has emerged as a promising therapeutic strategy for the treatment of cardiac diseases. Since the first cell transplant to patients, different types of (stem) cells have been studied. This study aims to provide a comprehensive review of different types of cells and their roles in cardiac cell-based therapy.
过去十年见证了心脏病治疗方面的许多进展；然而，许多慢性心力衰竭患者的生活质量较低。药物输送和心脏移植等治疗方法已被用于改善生活质量。细胞疗法和组织工程学最近作为一种新的治疗方法被引入医学领域。通过引入细胞治疗方法，心脏病的治疗取得了新的发展。基于证据，细胞疗法已成为治疗心脏疾病的一种有前途的治疗策略。自首次将细胞移植到患者体内以来，已经研究了不同类型的（干）细胞。本研究旨在全面综述不同类型的细胞及其在基于心脏细胞的治疗中的作用。
