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Diagnostic challenge: an atypical presentation of infective endocarditis.诊断难题:感染性心内膜炎的非典型表现。
BMJ Case Rep. 2021 Jan 25;14(1):e239994. doi: 10.1136/bcr-2020-239994.
2
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A man with dyspnea, chest pain and leukocytosis.一名患有呼吸困难、胸痛和白细胞增多症的男子。
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本文引用的文献

1
Time to Acute Kidney Injury in β-Lactam-Induced Acute Interstitial Nephritis.β-内酰胺类抗生素所致急性间质性肾炎发生急性肾损伤的时间
Kidney Int Rep. 2020 Apr 20;5(7):1068-1070. doi: 10.1016/j.ekir.2020.04.008. eCollection 2020 Jul.
2
Infective Endocarditis: A Contemporary Review.感染性心内膜炎:当代综述。
Mayo Clin Proc. 2020 May;95(5):982-997. doi: 10.1016/j.mayocp.2019.12.008. Epub 2020 Apr 13.
3
Morbidity from in-hospital complications is greater than treatment failure in patients with Staphylococcus aureus bacteraemia.金黄色葡萄球菌菌血症患者的院内并发症发病率高于治疗失败率。
BMC Infect Dis. 2018 Mar 5;18(1):107. doi: 10.1186/s12879-018-3011-2.
4
Tubulointerstitial nephritis: diagnosis, treatment, and monitoring.肾小管间质性肾炎:诊断、治疗与监测
Pediatr Nephrol. 2017 Apr;32(4):577-587. doi: 10.1007/s00467-016-3394-5. Epub 2016 May 7.
5
Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy.成人感染性心内膜炎诊断和抗生素治疗指南:英国抗菌化疗学会工作组报告。
J Antimicrob Chemother. 2012 Feb;67(2):269-89. doi: 10.1093/jac/dkr450. Epub 2011 Nov 14.
6
Recommendations for the practice of echocardiography in infective endocarditis.感染性心内膜炎超声心动图检查实践的建议。
Eur J Echocardiogr. 2010 Mar;11(2):202-19. doi: 10.1093/ejechocard/jeq004.
7
Patients at risk of complications of Staphylococcus aureus bloodstream infection.有金黄色葡萄球菌血流感染并发症风险的患者。
Clin Infect Dis. 2009 May 15;48 Suppl 4:S246-53. doi: 10.1086/598187.
8
Infective endocarditis.感染性心内膜炎。
BMJ. 2006 Aug 12;333(7563):334-9. doi: 10.1136/bmj.333.7563.334.
9
Validation of a modified Early Warning Score in medical admissions.改良早期预警评分在医疗入院患者中的验证
QJM. 2001 Oct;94(10):521-6. doi: 10.1093/qjmed/94.10.521.
10
Right-side endocarditis in injection drug users: review of proposed mechanisms of pathogenesis.注射吸毒者右侧心内膜炎:发病机制的相关研究综述
Clin Infect Dis. 2000 Feb;30(2):374-9. doi: 10.1086/313664.

诊断难题:感染性心内膜炎的非典型表现。

Diagnostic challenge: an atypical presentation of infective endocarditis.

机构信息

Cardiology, United Lincolnshire Hospitals NHS Trust, Lincoln, Lincolnshire, UK

Cardiology, United Lincolnshire Hospitals NHS Trust, Lincoln, Lincolnshire, UK.

出版信息

BMJ Case Rep. 2021 Jan 25;14(1):e239994. doi: 10.1136/bcr-2020-239994.

DOI:10.1136/bcr-2020-239994
PMID:33495170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7839874/
Abstract

It is recognised that infective endocarditis is frequently a challenging diagnosis to make, as it may present with a range of non-specific symptoms. A middle-aged man was admitted with an 8-day history of profuse non-bloody diarrhoea and vomiting. He had no medical history and no identifiable risk factors for infective endocarditis, and so this in combination with the patient's atypical symptoms presented a diagnostic challenge. The patient was eventually diagnosed with a right-sided infective endocarditis. This case report explores the events which led to this diagnosis and demonstrates a number of unique learning points. It also highlights the importance of maintaining an open mind and being prepared to revise an initial diagnosis in the face of medical uncertainty.

摘要

人们认识到,感染性心内膜炎的诊断常常具有挑战性,因为它可能表现出一系列非特异性症状。一名中年男子因 8 天来大量非血性腹泻和呕吐而入院。他没有既往病史,也没有可识别的感染性心内膜炎危险因素,因此,结合患者的非典型症状,这对诊断提出了挑战。该患者最终被诊断为右侧感染性心内膜炎。本病例报告探讨了导致该诊断的事件,并展示了一些独特的学习要点。它还强调了在面对医学不确定性时保持开放思维并准备修改初始诊断的重要性。