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Accidental actinomycin D overdosage in man, a case report.

作者信息

Choonara I A, Kendall-Smith S, Bailey C C

机构信息

Department of Paediatrics and Child Health, St. James's University Hospital, Leeds, England.

出版信息

Cancer Chemother Pharmacol. 1988;21(2):173-4. doi: 10.1007/BF00257367.

DOI:10.1007/BF00257367
PMID:3349565
Abstract

Although actinomycin D is a relatively old cytotoxic agent, relatively little is known about its toxicity in man in comparison with some of the newer cytotoxic agents that have been extensively investigated. We wish to describe a case where an overdose of actinomycin D was inadvertently administered.

摘要

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本文引用的文献

1
The toxicity of actinomycin D.放线菌素D的毒性。
Ann N Y Acad Sci. 1960 Oct 5;89:348-60. doi: 10.1111/j.1749-6632.1960.tb20158.x.
2
Actinomycin D toxicity in the treatment of trophoblastic disease: a comparison of the five-day course to single-dose administration.放线菌素D治疗滋养细胞疾病的毒性:五日疗程与单剂量给药的比较。
Gynecol Oncol. 1980 Feb;9(1):18-22. doi: 10.1016/0090-8258(80)90004-9.
3
Effect of actinomycin D on aldosterone-mediated changes in electrolyte excretion.
Am J Physiol. 1973 Feb;224(2):376-80. doi: 10.1152/ajplegacy.1973.224.2.376.
4
Hepatitis following actinomycin D and irradiation.放线菌素D与放疗后的肝炎
Proc R Soc Med. 1974 Aug;67(8):756-7. doi: 10.1177/003591577406700834.
5
Plasma ultrafiltrable magnesium in insulin dependent diabetics.胰岛素依赖型糖尿病患者的血浆可超滤镁
J Clin Pathol. 1987 Mar;40(3):294-7. doi: 10.1136/jcp.40.3.294.
6
A pharmacokinetically based phase I-II study of single-dose actinomycin D (NSC-3053).基于药代动力学的单剂量放线菌素D(NSC-3053)I-II期研究。
Cancer Treat Rep. 1976 Mar;60(3):289-91.
7
Single dose toxicity of actinomycin D (NSC-3053) in dogs.放线菌素D(NSC - 3053)对犬的单剂量毒性
Cancer Chemother Rep. 1975 Mar-Apr;59(2 Pt 1):447-9.
8
Actinomycin D in childhood acute lymphocytic leukemia.放线菌素D用于儿童急性淋巴细胞白血病
Cancer Treat Rep. 1978 May;62(5):829-31.