Ghazisaeedi Marjan, Mahmoodi Hamed, Arpaci Ibrahim, Mehrdar Siavash, Barzegari Saeed
Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Health Information Management Research Center, Kashan University Medical Sciences, Kashan, Iran.
Int J Ment Health Addict. 2022;20(3):1824-1833. doi: 10.1007/s11469-021-00483-5. Epub 2021 Jan 20.
This study aimed to investigate the validity, reliability, and optimal cut-off points for the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-9 (PHQ-9), and Well-being Index (WHO-5) to screen mild depression among 400 Iranian students who completed these tools and Beck Depression Inventory (BDI-13). Further, a psychiatrist diagnosed the depression by using the "Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders." The validity and internal consistency of tools assessed and the accuracy were computed using the receiver operating characteristic (ROC) and area under the curve (AUC). The internal consistency values of PHQ-2, PHQ-9, and WHO-5 were .73, .88, and .94, respectively. The PHQ-2 (.53), PHQ-9 (.60), and WHO-5 (.54) were significantly associated with the BDI. The PHQ-2, PHQ-9, and WHO-5 had optimal cut-off points of 2, 5, and 9 with an AUC of .809, .851, and .823, respectively. Based on these findings, it is recommended to use the PHQ-9 for mild depression screening among medical university students in Iran because of its high sensitivity and specificity.
本研究旨在调查患者健康问卷-2（PHQ-2）、患者健康问卷-9（PHQ-9）和幸福感指数（WHO-5）在400名完成这些量表及贝克抑郁量表（BDI-13）的伊朗学生中筛查轻度抑郁的有效性、可靠性及最佳临界点。此外，一名精神科医生使用《精神障碍诊断与统计手册》的“结构化临床访谈”对抑郁进行诊断。通过计算受试者工作特征曲线（ROC）和曲线下面积（AUC）评估工具的有效性和内部一致性，并计算准确性。PHQ-2、PHQ-9和WHO-5的内部一致性值分别为0.73、0.88和0.94。PHQ-2（0.53）、PHQ-9（0.60）和WHO-5（0.54）与BDI显著相关。PHQ-2、PHQ-9和WHO-5的最佳临界点分别为2、5和9，AUC分别为0.809、0.851和0.823。基于这些发现，建议在伊朗医科大学学生中使用PHQ-9进行轻度抑郁筛查，因其具有较高的敏感性和特异性。
