Medical University of South Carolina, Speech-Language Pathology Program, Department of Rehabilitation Sciences, College of Health Professions, Charleston, South Carolina, United States.
Department of Public Health Sciences, Hollings Cancer Center Biostatistics Shared Resource, Medical University of South Carolina, Charleston, South Carolina, United States.
Head Neck. 2021 May;43(5):1398-1408. doi: 10.1002/hed.26609. Epub 2021 Jan 25.
The aim of the study was to determine the link between frequency of optimal respiratory-swallow coordination, swallowing impairment, and airway invasion in head and neck cancer (HNC) patients.
A cross-sectional study of a heterogeneous group of HNC patients (49), precancer (N = 30) or postcancer treatment (N = 29), participated in a single Modified Barium Swallow Study (MBSS) with synchronized respiratory data.
Spearman correlation coefficients revealed significant negative correlations between optimal respiratory-swallow phase pattern and objective measures of swallowing impairment: penetration-aspiration scale max, pharyngeal total, and oral total scores with Spearman correlation coefficients of -0.53 (z .001), -0.50 (P < .001), and -0.43 (P = .002), respectively. Optimal respiratory-swallow pattern was significantly decreased (P = .03) in patients after cancer treatment compared with another patient group before cancer treatment.
These findings indicate that as the percentage of optimal respiratory-swallow phase patterns increase, swallowing impairment decreases in the HNC patient population.
本研究旨在确定头颈部癌症（HNC）患者最佳呼吸-吞咽协调性频率、吞咽障碍和气道侵犯之间的关系。
对一组异质的 HNC 患者（49 例）进行了一项横断面研究，包括癌前病变（N=30）和癌症治疗后（N=29）患者，所有患者均进行了一次改良钡吞咽研究（MBSS），并同步记录呼吸数据。
Spearman 相关系数显示，最佳呼吸-吞咽时相模式与吞咽障碍的客观测量指标之间存在显著负相关：渗透-吸入量表最大值、咽部总分和口腔总分的 Spearman 相关系数分别为-0.53（z.001）、-0.50（P < .001）和-0.43（P=.002）。与另一组癌症治疗前的患者相比，癌症治疗后的患者最佳呼吸-吞咽时相模式显著减少（P=.03）。
这些发现表明，在 HNC 患者群体中，随着最佳呼吸-吞咽时相模式的百分比增加，吞咽障碍减少。
