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不同物种之间单血小板生物物理学存在显著差异，但在凝血形成过程中这种差异会减弱。

Significant differences in single-platelet biophysics exist across species but attenuate during clot formation.

作者信息

Oshinowo Oluwamayokun, Copeland Renee, Sakurai Yumiko, Fay Meredith E, Petrich Brian G, Leong Traci, Brainard Benjamin, Lam Wilbur A

机构信息

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA.

Department of Pediatrics, Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta, Emory University School of Medicine, Emory University, Atlanta, GA.

出版信息

Blood Adv. 2021 Jan 26;5(2):432-437. doi: 10.1182/bloodadvances.2020003755.

DOI:10.1182/bloodadvances.2020003755
PMID:33496738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7839362/
Abstract

Human, canine, ovine, and porcine platelets exhibit disparate biophysical signatures, whereas human and murine platelets are similar. Multiple biophysical parameters integrate during clot formation, measured by bulk clot contraction, and attenuate biophysical differences.

摘要

人类、犬类、绵羊和猪的血小板表现出不同的生物物理特征，而人类和小鼠的血小板则相似。在凝块形成过程中，多个生物物理参数会整合在一起，通过整体凝块收缩来测量，并减弱生物物理差异。

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本文引用的文献

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J Thromb Haemost. 2020-2

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