Primary Cilia Dyskinesia Unit, School of Medicine, University of Thessaly, Thessaly, Greece.
Pediatric Asthma and Cough Centre, Instituti Ospedalieri Bergamaschi, University and Research Hospitals, Bergamo, Italy.
Lung. 2021 Feb;199(1):7-12. doi: 10.1007/s00408-021-00419-9. Epub 2021 Jan 26.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects both children and adults but epidemiological and clinical data demonstrate that children are less likely to have a severe disease course or die. Furthermore, asthmatic children show less severe disease manifestations when infected with SARS-CoV-2 comparing to adults. This review focuses on SARS-CoV-2 and childhood asthma interaction and aims at summarizing the current knowledge of the potential mechanisms that ameliorate disease symptomatology in asthmatic children.
严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）可感染儿童和成人，但流行病学和临床数据表明，儿童患重病或死亡的可能性较小。此外，与成年人相比，感染 SARS-CoV-2 的哮喘儿童的疾病表现较轻。本综述重点关注 SARS-CoV-2 与儿童哮喘的相互作用，并旨在总结减轻哮喘儿童疾病症状的潜在机制的现有知识。
