Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Room 12N-37, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands.
Saliva Clinic of the Dutch Institute for Salivary Research, Bunschoten, Netherlands.
Clin Oral Investig. 2021 Jun;25(6):4031-4043. doi: 10.1007/s00784-020-03734-2. Epub 2021 Jan 26.
Recently, it was shown that the Regional Oral Dryness Inventory (RODI) could determine differences in dry-mouth perception at different intra-oral locations. The main aim of this study was to determine whether the RODI might help to discriminate between various causes of oral dryness in dry-mouth patients. The second aim was to ascertain whether the RODI could become an additional diagnostic tool in dry-mouth patients.
Data were collected retrospectively from patients who visited a specialized saliva clinic. Salivary flow rates, Xerostomia Inventory scores, and RODI scores were extracted from the medical records. Patients were stratified into subgroups according to their health status.
Five hundred twenty-eight patients participated in this study (mean age of 59.6 ± 16.0 years; 68.4% female). Specific patient groups differed with regard to the region of the mouth they experienced as the most and least dry. The posterior palate was the area perceived as most dry by controls and Sjögren patients. In patients using limited or multiple medications, it was the anterior tongue. RODI scores also differed significantly among dry-mouth patient groups: whereas controls and patients using limited medication had the lowest RODI scores and experienced less intra-oral dryness, Sjögren patients had the highest RODI scores.
Our use of the RODI questionnaire showed that perceived intra-oral dryness differed between the various dry-mouth patients.
The RODI can be a valuable clinical diagnostic tool in dry-mouth diagnostics, in which it can be used to discriminate between the various causes of oral dryness in patients.
最近的研究表明，区域口腔干燥量表（RODI）可以确定口腔不同部位干燥感的差异。本研究的主要目的是确定 RODI 是否有助于区分口干患者的各种口干原因。第二个目的是确定 RODI 是否可以成为口干患者的另一种诊断工具。
从就诊于专门唾液诊所的患者中回顾性收集数据。从病历中提取唾液流量、口干量表和 RODI 评分。根据患者的健康状况将其分为亚组。
本研究共纳入 528 例患者（平均年龄 59.6±16.0 岁，女性占 68.4%）。特定的患者群体在他们认为最干燥和最不干燥的口腔区域方面存在差异。对照组和干燥综合征患者的后腭被认为是最干燥的区域。在使用有限或多种药物的患者中，干燥的区域在前舌。RODI 评分在口干患者群体中也存在显著差异：对照组和使用有限药物的患者的 RODI 评分最低，口腔内干燥感最小，而干燥综合征患者的 RODI 评分最高。
我们使用 RODI 问卷表明，不同口干患者的口腔内干燥感存在差异。
RODI 可以成为口干诊断的有价值的临床诊断工具，可用于区分患者的各种口干原因。
