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异基因造血干细胞移植中的供受者故事。

Donor-Recipient Story in Allogeneic Hematopoietic Stem Cell Transplantation.

机构信息

Stem Cell Club, Toronto, ON M2H 3L2, Canada.

Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.

出版信息

Curr Oncol. 2021 Jan 24;28(1):689-692. doi: 10.3390/curroncol28010067.

Abstract

Patients with a variety of blood, immune, and metabolic disorders may require an allogeneic hematopoietic stem cell transplant as part of their treatment. However, over 70% of these patients do not have a matched sibling donor and require an alternative donor, such as a matched unrelated donor. We present a multi-part story of a Canadian stem cell recipient who underwent transplantation for treatment of refractory chronic myelogenous leukemia, and the matched unrelated donor who saved his life. The story segments feature excerpts from interviews with the donor and the recipient, along with representative images of both storytellers. The excerpts were optimized for publication on social media and were arranged to build a story arc that parallels the journey of the donor and recipient together. This donor-recipient story may serve as a resource to help raise awareness about stem cell donation and to encourage eligible individuals to register as donors. The story is one of several developed by Why We Swab, a library of stories in stem cell donation in Canada (Facebook, Twitter, and Instagram; @WhyWeSwab) to support the recruitment of committed unrelated donors.

摘要

患有各种血液、免疫和代谢紊乱的患者可能需要异体造血干细胞移植作为其治疗的一部分。然而,超过 70%的这些患者没有匹配的兄弟姐妹供体,需要替代供体,如匹配的无关供体。我们讲述了一个加拿大干细胞接受者的多部分故事,他因治疗难治性慢性粒细胞白血病而接受了移植,以及挽救他生命的匹配无关供体。故事片段包括对供体和接受者的采访摘录,以及两位讲述者的代表性图片。这些摘录经过优化,可在社交媒体上发布,并按照构建故事弧的方式进行安排,该故事弧与供体和接受者的旅程平行。这个供体-接受者的故事可以作为一种资源,帮助提高人们对干细胞捐赠的认识,并鼓励符合条件的个人注册为捐赠者。这个故事是加拿大干细胞捐赠中的 Why We Swab(Facebook、Twitter 和 Instagram;@WhyWeSwab)开发的几个故事之一,旨在支持招募有承诺的无关供体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/458f/7924398/a39fdcf132cb/curroncol-28-00067-g001.jpg

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