Mirzae Yoni, Rubinstein Boris Y, Morozov Konstantin I, Leshansky Alexander M
Department of Mathematics, Technion-Israel Institute of Technology, Haifa, Israel.
Stowers Institute for Medical Research, Kansas City, MO, United States.
Front Robot AI. 2020 Oct 29;7:595777. doi: 10.3389/frobt.2020.595777. eCollection 2020.
The emergent interest in artificial nanostructures that can be remotely navigated a specific location in a fluidic environment is motivated by the enormous potential this technology offers to biomedical applications. Originally, bio-inspired micro-/nanohelices driven by a rotating magnetic field were proposed. However, fabrication of 3D helical nanostructures is complicated. One idea to circumvent complex microfabrication is to use 1D soft magnetic nanowires that acquire chiral shape when actuated by a rotating field. The paper describes the comprehensive numerical approach for modeling propulsion of externally actuated soft magnetic nanowires. The proposed bead-spring model allows for arbitrary filament geometry and flexibility and takes rigorous account of intra-filament hydrodynamic interactions. The comparison of the numerical predictions with the previous experimental results on propulsion of composite two-segment (Ni-Ag) nanowires shows an excellent agreement. Using our model we could substantiate and rationalize important and previously unexplained details, such as bidirectional propulsion of three-segment (Ni-Ag-Au) nanowires.
对可在流体环境中远程导航至特定位置的人工纳米结构的新兴兴趣，源于该技术在生物医学应用中所具有的巨大潜力。最初，有人提出了由旋转磁场驱动的受生物启发的微/纳米螺旋结构。然而，三维螺旋纳米结构的制造过程很复杂。规避复杂微制造的一个想法是使用一维软磁纳米线，这种纳米线在旋转场驱动时会获得手性形状。本文描述了用于模拟外部驱动软磁纳米线推进的综合数值方法。所提出的珠簧模型允许任意的细丝几何形状和柔韧性，并严格考虑了细丝内的流体动力相互作用。数值预测结果与先前关于复合两段式（镍 - 银）纳米线推进的实验结果的比较显示出极佳的一致性。使用我们的模型，我们可以证实并合理解释重要且先前无法解释的细节，比如三段式（镍 - 银 - 金）纳米线的双向推进。
