Respiratory Medicine Unit, Department of Clinical and Experimental Sciences, University of Brescia.
Department of Molecular and Translational Medicine. University of Brescia and Pathology Unit, ASST Spedali Civili di Brescia.
Monaldi Arch Chest Dis. 2021 Jan 25;91(1). doi: 10.4081/monaldi.2021.1520.
Angiosarcoma is a rare malignancy of vascular origin, mostly originating from skin, soft tissues, and breast, but rarely also from the pleura. We present the case of a 55-year-old man who referred to our hospital for a spontaneous bilateral hemothorax. The CT angiography did not show any source of active bleeding; plus, no pleural or lung masses were observable. Cytological and microbiological analyses made on a sample of pleural fluid resulted negative. Despite numerous blood transfusions and thoracenteses, the patient deceased from hemorrhagic shock ten days later and the diagnosis of primary pleural epithelioid angiosarcoma was obtained only by autopsy. Additionally, we present a review of the literature about primary pleural angiosarcomas.
血管肉瘤是一种罕见的血管来源的恶性肿瘤，主要起源于皮肤、软组织和乳房，但也很少来自胸膜。我们报告了一例 55 岁男性患者，因自发性双侧血胸就诊于我院。CT 血管造影未显示任何活动性出血源；此外，也没有观察到胸膜或肺部肿块。胸膜液样本的细胞学和微生物分析结果为阴性。尽管多次输血和胸腔穿刺，患者仍因失血性休克十天后死亡，仅通过尸检获得了原发性胸膜上皮样血管肉瘤的诊断。此外，我们还对原发性胸膜血管肉瘤的文献进行了回顾。
