诱导免疫重建炎症综合征还是抑制它：抗逆转录病毒时代的龟分枝杆菌谱。
To Induce Immune Reconstitution Inflammatory Syndrome or Suppress It: The Spectrum of Mycobacterium genavense in the Antiretroviral Era.
机构信息
National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
St James's Hospital, Dublin, Ireland.
出版信息
Clin Infect Dis. 2021 Jan 27;72(2):315-318. doi: 10.1093/cid/ciaa753.
Abstract
Mycobacterium genavense is a challenging opportunistic pathogen to diagnose and manage in patients with human immunodeficiency virus (HIV). Persistent immunosuppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses. We describe 3 cases of M. genavense in patients with HIV representing the spectrum between disease burden and strength of immune response.
摘要
产色分枝杆菌是一种具有挑战性的机会性病原体，在人类免疫缺陷病毒（HIV）患者中诊断和治疗具有一定难度。持续的免疫抑制或延长的免疫重建炎症综合征可能导致复杂的临床病程。我们描述了 3 例 HIV 患者中的产色分枝杆菌感染病例，代表了疾病负担和免疫反应强度之间的谱。
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