Schulze-Koops Hendrik, Krüger Klaus, Hoyer Bimba Franziska, Leipe Jan, Iking-Konert Christof, Specker Christof
Division of Rheumatology and Clinical Immunology, Department of Medicine IV, Ludwig-Maximilians-Universität München.
Rheumatologisches Praxiszentrum München, München.
Rheumatology (Oxford). 2021 May 14;60(5):2128-2133. doi: 10.1093/rheumatology/keab072.
A few days after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was declared a pandemic, the German Society for Rheumatology (DGRh) compiled the first group of recommendations for the care of patients with inflammatory rheumatic diseases in light of SARS-CoV-2/coronavirus disease 2019 (COVID-19). These first recommendations were based on an expert consensus and were largely non-evidence-based. Now that the first scientific data from registries, cross-sectional studies, case reports and case series are available, the DGRh has developed a timely update. This update is based on a literature search of publications available through 15 June 2020 and addresses preventive measures (such as hygiene measures or vaccinations) and the use of immunomodulatory/immunosuppressive drugs. Driven by the commitment to let patients benefit from these new evidence-based recommendations as quickly as possible, the DGRh published the update in German on its homepage and in the Zeitschrift für Rheumatologie immediately after completion. Here we report the key recommendations to make them available to the international community, provide the scientific methodology used to develop the recommendations, give additional thoughts and advice for the management of patients with rheumatic diseases during the COVID-19 pandemic and discuss our recommendations in the context of other international recommendations.
在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染被宣布为大流行几天后,德国风湿病学会(DGRh)根据SARS-CoV-2/2019冠状病毒病(COVID-19)编制了首批针对炎性风湿性疾病患者护理的建议。这些首批建议基于专家共识,且很大程度上缺乏循证依据。鉴于现在已有来自登记处、横断面研究、病例报告和病例系列的首批科学数据,DGRh及时进行了更新。此次更新基于对截至2020年6月15日可获取的出版物的文献检索,并涉及预防措施(如卫生措施或疫苗接种)以及免疫调节/免疫抑制药物的使用。出于让患者尽快从这些新的循证建议中受益的承诺,DGRh在完成更新后立即在其主页上以德语发布,并在《风湿病学杂志》上发表。在此,我们报告关键建议,以便国际社会了解,提供制定这些建议所采用的科学方法,针对COVID-19大流行期间风湿病患者的管理给出更多思考和建议,并在其他国际建议的背景下讨论我们的建议。