Department of Surgery, University Hospital "Dr José J. Aguirre", Faculty of Medicine, University of Chile, Santiago, Chile.
Arq Bras Cir Dig. 2021 Jan 25;33(4):e1553. doi: 10.1590/0102-672020200004e1553. eCollection 2021.
Gastroesophageal reflux (GER) is one of the most common indications for conversion of sleeve gastrectomy (LSG) to laparoscopic Roux-en-Y gastric bypass (LRYGBP). Objective evaluations are necessary in order to choose the best definitive treatment for these patients.
To present and describe the findings of the objective studies for gastroesophageal reflux disease performed before LSG conversion to LRYGBP in order to support the indication for surgery.
Thirty-nine non-responder patients to proton pump inhibitors treatment after LSG were included in this prospective study. They did not present GER symptoms, esophagitis or hiatal hernia before LSG. Endoscopy, radiology, manometry, 24 h pH monitoring were performed.
The mean time of appearance of reflux symptoms was 26.8+24.08 months (8-71). Erosive esophagitis was found in 33/39 symptomatic patients (84.6%) and Barrett´s esophagus in five. (12.8%). Manometry and acid reflux test were performed in 38/39 patients. Defective lower esophageal sphincter function was observed independent the grade of esophagitis or Barrett´s esophagus. Pathologic acid reflux with elevated DeMeester´s scores and % of time pH<4 was detected in all these patients. more significant in those with severe esophagitis and Barrett´s esophagus. Radiologic sleeve abnormalities were observed in 35 patients, mainly cardia dilatation (n=18) and hiatal hernia (n=11). Middle gastric stricture was observed in only six patients.
Patients with reflux symptoms and esophagitis or Barrett´s esophagus after SG present defective lower esophageal sphincter function and increased acid reflux. These conditions support the indication of conversion to LRYGBP.
胃食管反流(GER)是袖状胃切除术(LSG)转为腹腔镜 Roux-en-Y 胃旁路术(LRYGBP)的最常见指征之一。为了为这些患者选择最佳的确定性治疗方法,有必要进行客观评估。
介绍并描述 LSG 转为 LRYGBP 前用于胃食管反流病的客观研究结果,以支持手术指征。
本前瞻性研究纳入了 39 例 LSG 后质子泵抑制剂治疗无效的非应答者。他们在 LSG 前没有 GER 症状、食管炎或食管裂孔疝。进行了内镜检查、影像学检查、测压、24 小时 pH 监测。
反流症状出现的平均时间为 26.8+24.08 个月(8-71)。39 例有症状患者中有 33/39 例(84.6%)存在糜烂性食管炎,5 例(12.8%)存在 Barrett 食管。38/39 例患者进行了测压和酸反流试验。独立于食管炎或 Barrett 食管的严重程度,均观察到下食管括约肌功能不全。所有这些患者均存在病理性酸反流,DeMeester 评分和 pH<4 的时间百分比升高。在严重食管炎和 Barrett 食管患者中更为显著。35 例患者观察到胃袖套异常,主要为贲门扩张(n=18)和食管裂孔疝(n=11)。仅 6 例患者存在胃中段狭窄。
SG 后出现反流症状和食管炎或 Barrett 食管的患者存在下食管括约肌功能不全和酸反流增加。这些情况支持转为 LRYGBP 的指征。