Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Department of Anesthesiology, Critical Care Medicine, Emergency Medicine and Pain Therapy, Campus Kassel of the University of Southampton, Kassel, Germany.
Blood Purif. 2021;50(6):968-970. doi: 10.1159/000512983. Epub 2021 Jan 27.
In recent years, extracorporeal hemadsorption (HA) techniques capable of adsorbing pro- and anti-inflammatory cytokines are increasingly used in various clinical situations. The therapeutic benefit of cytokine elimination likely depends on timing. Although treatment seems to be most effective when started within the first 24 h, therapy is often delayed as it must be combined with another extracorporeal circuit. Thus, using a pumpless extracorporeal HA technique might be a valuable option in order to expedite the commencement of cytokine elimination in critically ill patients.
近年来，能够吸附促炎和抗炎细胞因子的体外血液吸附 (HA) 技术在各种临床情况下得到了越来越多的应用。细胞因子消除的治疗益处可能取决于时机。虽然在最初的 24 小时内开始治疗似乎最有效，但由于必须与另一个体外回路结合使用，因此治疗常常会被延迟。因此，使用无泵体外血液吸附技术可能是一种有价值的选择，以便在危重病患者中加快开始细胞因子消除的进程。
