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Tocilizumab for the treatment of COVID-19.

作者信息

Fernández-Ruiz Mario, López-Medrano Francisco, Aguado José María

机构信息

Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Instituto de Investigación Sanitaria Hospital "12 de Octubre" (Imas12), Madrid, Spain.

Department of Medicine, School of Medicine, Universidad Complutense, Madrid, Spain.

出版信息

Expert Opin Biol Ther. 2021 Apr;21(4):431-434. doi: 10.1080/14712598.2021.1880563. Epub 2021 Jan 27.

DOI:10.1080/14712598.2021.1880563
PMID:33504238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7852257/
Abstract
摘要

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本文引用的文献

1
Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia.托珠单抗治疗新冠肺炎合并肺炎住院患者的疗效。
N Engl J Med. 2021 Jan 7;384(1):20-30. doi: 10.1056/NEJMoa2030340. Epub 2020 Dec 17.
2
Cytokine Storm.细胞因子风暴
N Engl J Med. 2020 Dec 3;383(23):2255-2273. doi: 10.1056/NEJMra2026131.
3
Pulmonary vascular improvement in severe COVID-19 patients treated with tocilizumab.托珠单抗治疗重症 COVID-19 患者的肺血管改善。
Immunol Lett. 2020 Dec;228:122-128. doi: 10.1016/j.imlet.2020.10.009. Epub 2020 Nov 5.
4
Efficacy of Tocilizumab in Patients Hospitalized with Covid-19.托珠单抗治疗 COVID-19 住院患者的疗效。
N Engl J Med. 2020 Dec 10;383(24):2333-2344. doi: 10.1056/NEJMoa2028836. Epub 2020 Oct 21.
5
Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical Trial.托珠单抗对比常规治疗用于 COVID-19 成人患者伴中重度肺炎的随机临床试验
JAMA Intern Med. 2021 Jan 1;181(1):32-40. doi: 10.1001/jamainternmed.2020.6820.
6
Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial.托珠单抗与标准治疗对 COVID-19 肺炎住院患者临床恶化的影响：一项随机临床试验。
JAMA Intern Med. 2021 Jan 1;181(1):24-31. doi: 10.1001/jamainternmed.2020.6615.
7
Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.COVID-19 重症患者早期使用托珠单抗治疗与死亡率的关联。
JAMA Intern Med. 2021 Jan 1;181(1):41-51. doi: 10.1001/jamainternmed.2020.6252.
8
Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes.严重和危重新冠肺炎中的细胞因子升高：快速系统评价、荟萃分析，并与其他炎症综合征比较。
Lancet Respir Med. 2020 Dec;8(12):1233-1244. doi: 10.1016/S2213-2600(20)30404-5. Epub 2020 Oct 16.
9
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19).托珠单抗或皮质类固醇治疗伴有炎症过高状态的 COVID-19 患者：一项多中心队列研究（SAM-COVID-19）。
Clin Microbiol Infect. 2021 Feb;27(2):244-252. doi: 10.1016/j.cmi.2020.08.010. Epub 2020 Aug 27.
10
Tocilizumab in patients with severe COVID-19: a retrospective cohort study.托珠单抗治疗重症新型冠状病毒肺炎患者：一项回顾性队列研究
Lancet Rheumatol. 2020 Aug;2(8):e474-e484. doi: 10.1016/S2665-9913(20)30173-9. Epub 2020 Jun 24.