Dos Santos Michelli, Ferreira André V F, da Silva Jonatas O, Nogueira Laís M, Machado Juliana M, Francisco Mariana F C, da Paz Mariana C, Giunchetti Rodolfo C, Galdino Alexsandro S
Laboratório de Biotecnologia de Microrganismos, Universidade Federal de São João Del-Rei, Sebastião Gonçalves Coelho, 400, 355901-296, Divinópolis, MG, Brazil.
Laboratório de Nano- Biotecnologia & Bioativos, Universidade Federal de São João Del-Rei, Sebastião Gonçalves Coelho, 400, 355901-296, Divinópolis, MG, Brazil.
Recent Pat Biotechnol. 2021;15(1):12-24. doi: 10.2174/1872208315666210127085404.
Coronaviruses have caused outbreaks of respiratory disease since the beginning of the 21st century, representing a significant threat to public health. Together, the severe acute respiratory syndrome coronavirus (SARS-CoV), the respiratory syndrome coronavirus (MERS-CoV), and, more recently, the novel coronavirus (SARS-CoV-2) have caused a large number of deaths around the world. Thus, investments in research and the development of strategies aimed at diagnosing, treating, and preventing these infections are urgently needed.
The objective of this study was to analyze the patents that address pathogenic coronaviruses in Google Patents databases in the last year (2019-2020).
The search strategy was carried out in April 2020, based on the keywords "SARS", "SARS-CoV", "MERS", "MERS-CoV", "SARS-CoV-2" and "COVID-19. Out of the patents examined, 25 were selected for a short description in this study.
A total of 191 patents were analyzed, 149 of which were related to SARS-CoV, and 29 and 12 were related to MERS-CoV and SARS- CoV2, respectively. The patents addressed the issues of diagnosis, therapeutic agents, prevention and control, along with other applications.
Several promising strategies have been documented in intellectual property databases favoring the need for further studies on the pathogenesis and optimization of the diagnosis and therapeutic treatment for these emerging infections.
自21世纪初以来，冠状病毒已引发呼吸道疾病疫情，对公众健康构成重大威胁。严重急性呼吸综合征冠状病毒（SARS-CoV）、中东呼吸综合征冠状病毒（MERS-CoV）以及最近的新型冠状病毒（SARS-CoV-2）共同在全球造成了大量死亡。因此，迫切需要投资于旨在诊断、治疗和预防这些感染的研究及策略开发。
本研究的目的是分析去年（2019 - 2020年）谷歌专利数据库中涉及致病性冠状病毒的专利。
检索策略于2020年4月实施，基于关键词“SARS”、“SARS-CoV”、“MERS”、“MERS-CoV”、“SARS-CoV-2”和“COVID-19”。在所审查的专利中，本研究挑选了25项进行简短描述。
共分析了191项专利，其中149项与SARS-CoV相关，29项和12项分别与MERS-CoV和SARS-CoV-2相关。这些专利涉及诊断、治疗药物、预防和控制等问题以及其他应用。
知识产权数据库中记录了几种有前景的策略，这支持了对这些新出现感染的发病机制以及诊断和治疗优化进行进一步研究的必要性。
