Delhi Pharmaceutical Sciences and Research University, New Delhi-110017, India.
Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Curr Pharm Des. 2021;27(3):423-439. doi: 10.2174/1381612826666200720233947.
Protecting intellectual property rights are important and particularly pertinent for inventions that are an outcome of rigorous research and development. While the grant of patents is subject to establishing novelty and inventive step, it further indicates the technological development and is helpful for researchers working in the same technical domain. The aim of the present research work is to map the existing work through an analysis of patent literature in the field of Coronaviruses (CoV), particularly COVID-19 (2019-nCoV). CoV is a large family of viruses known to cause illness in humans and animals, particularly known for causing respiratory infections, as evidenced in earlier times, such as in MERS i.e., Middle East Respiratory Syndrome; and SRS i.e., Severe Acute Respiratory Syndrome. A recently identified novel-coronavirus, known as COVID-19, has caused pandemic situations across the globe.
To expand the analysis of patents related to CoV and 2019-nCoV, an evaluation has been conducted by patenting trends of particular strains of identified CoV diseases by present legal status, main concerned countries via the earliest priority years and its assignee types and inventors of identified relevant patents. The global patent documents were analyzed to check the scope of claims along with focuses and trends of the published patent documents for the entire CoV family, including 2019-nCoV through the present landscape.
To extract the results, the Derwent Innovation database was used by a combination of different keystrings. Approximately 3800 patents were obtained and further scrutinized and analyzed. The present write-up also discusses the recent progress of patent applications in a period of the year 2010 to 2020 (present) along with the recent developments in India for the treatment options for CoV and 2019-nCoV.
Present analysis showed that key areas of the inventions were the vaccines and diagnostic kits apart from the composition for the treatment of CoV. It was also observed that no specific vaccine treatments are available for the treatment of 2019-nCov; however, developing novel chemical or biological drugs and kits for early diagnosis, prevention, and disease management is the primary governing topic among the patented inventions. The present study also indicates potential research opportunities for the future, particularly to combat 2019-nCoV.
The present paper analyzes the existing patents in the field of Coronaviruses and 2019-nCoV and suggests a way forward for the effective contribution in this upcoming research area. From the trend analysis, an increase in the filing of the overall trend of patent families was observed for a period of 2010 to the current year. This multifaceted analysis of identified patent literature provides an understanding of the focuses on present ongoing research and a grey area in terms of the trends of technological innovations in disease management in patients with CoV and 2019-nCoV. Furthermore, the findings and outcome of the present study offer insights for the proposed research and innovation opportunities and provide actionable information in order to facilitate policymakers, academia, research-driven institutes and also investors to make better decisions regarding programmed steps for research and development for the diagnosis, treatment and taking preventive measures for CoV and 2019-nCoV. The present article also emphasizes the need for future development and the role of academia and collaboration with industry for speedy research with a rationale.
保护知识产权对于严格的研发成果的发明尤为重要。虽然专利的授予取决于新颖性和创造性步骤，但它进一步表明了技术发展，有助于同一技术领域的研究人员。本研究工作的目的是通过对冠状病毒（CoV）领域的专利文献进行分析，特别是对 COVID-19（2019-nCoV）进行现有工作的映射。CoV 是一大类已知会导致人类和动物疾病的病毒，特别是已知会引起呼吸道感染，早期就有证据表明，例如 MERS（中东呼吸综合征）和 SRS（严重急性呼吸综合征）。最近发现的一种新型冠状病毒，称为 COVID-19，已在全球范围内造成大流行。
为了扩大与 CoV 和 2019-nCoV 相关的专利分析，通过目前的法律地位、主要关注国家通过最早的优先权年及其受让人类型和鉴定相关专利的发明人，对特定 CoV 疾病株的专利趋势进行了评估。对全球专利文献进行了分析，以检查整个 CoV 家族（包括 2019-nCoV）的专利文献的范围、重点和趋势，以及目前的情况。
为了提取结果，使用了不同关键字串的 Derwent Innovation 数据库。获得了大约 3800 项专利，并对其进行了进一步的审查和分析。本报告还讨论了 2010 年至 2020 年（目前）期间在印度针对 CoV 和 2019-nCoV 的治疗方案的专利申请的最新进展。
目前的分析表明，发明的重点领域是疫苗和诊断试剂盒，除了 CoV 的治疗组合物。还观察到，目前尚无针对 2019-nCov 的特定疫苗治疗方法；然而，开发新型化学或生物药物以及早期诊断、预防和疾病管理试剂盒是专利发明的主要主题。本研究还为未来的研究提供了潜在的机会，特别是针对 2019-nCoV 的研究。
本文分析了冠状病毒和 2019-nCoV 领域的现有专利，并为在这一即将到来的研究领域的有效贡献提出了前进的道路。从趋势分析来看，2010 年至当前年度，整个专利家族的整体趋势的专利申请数量有所增加。对已鉴定专利文献的这种多方面分析，有助于了解目前正在进行的研究的重点以及在 CoV 和 2019-nCoV 患者的疾病管理方面技术创新趋势方面的空白领域。此外，本研究的结果和结果为拟议的研究和创新机会提供了见解，并提供了可操作的信息，以便为政策制定者、学术界、以研究为导向的机构以及投资者提供便利，为 CoV 和 2019-nCoV 的诊断、治疗和预防措施制定研究和开发计划做出更好的决策。本文还强调了未来发展的必要性以及学术界的作用以及与行业的合作，以合理的理由进行快速研究。
