Internal Medicine, Mount Sinai Health System, New York City, New York, USA
ENT and Head and Neck, University College Hospital, London, UK.
BMJ Case Rep. 2021 Jan 27;14(1):e240386. doi: 10.1136/bcr-2020-240386.
Miller Fisher syndrome (MFS), an acute demyelinating neuropathy, is characterised by a triad of areflexia, ataxia and ophthalmoplegia. It is the most common variant of Guillain-Barre Syndrome (GBS). In about 5.6%-7.1% of MFS cases, patients also suffer from progressive motor weakness of the limbs. This condition is termed MFS/GBS overlap syndrome. Whether it is in MFS or GBS, bilateral vocal cord paralysis (BVCP) is a rare manifestation with limited cases reported in the literature. We report an extremely rare case where a 65-year-old man developed BVCP in an MFS/GBS overlap syndrome. We have also reviewed previous case reports in the literature for comparison.
米勒费雪综合征（MFS）是一种急性脱髓鞘性神经病，其特征是三联征：反射消失、共济失调和眼肌麻痹。它是吉兰-巴雷综合征（GBS）最常见的变异型。在大约 5.6%-7.1%的 MFS 病例中，患者还会出现四肢进行性肌无力。这种情况被称为 MFS/GBS 重叠综合征。无论是在 MFS 还是 GBS 中，双侧声带麻痹（BVCP）都是一种罕见的表现，文献中报道的病例有限。我们报告了一例非常罕见的 MFS/GBS 重叠综合征患者出现 BVCP。我们还对文献中的以往病例报告进行了回顾性比较。
